Registration Dossier
Registration Dossier
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EC number: 221-904-3 | CAS number: 3275-24-9
Endpoint summary
Administrative data
Description of key information
Titanium tetrakic(dimethylammonium) is an organometalic liquid with an pH > 11. The substance is classified as corrosive (Skin Corr 1B, H314 and Eye Damage 1, H 318). Additionally, titanium tetrakic(dimethylammonium) can only be handled in air-free environments. It is a flammable liquid and extremely unstable (see also chapter 1.2 or 5.1.2 or 13). Within seconds, it reacts violently in contact with moisture or water. The decomposition products are dimethylamine and titanium oxide. Dimethylamine is a highly flammable gas, but dimethylamine is well water soluble, highly basic, and corrosive to skin and eyes. In an acute inhalation toxicity study with dimethylamine (Steinhagen et al.), severe corrosive and necrotic effects were observed on eyes, skin, and mucous nasal membranes
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is a strong acid (pH ≤ 2.0) or base (pH ≥ 11.5) and the available information indicates that it should be classified as skin corrosion (Category 1, 1A, 1B or 1C)
- Justification for type of information:
- Titanium tetrakic(dimethylammonium) is an organometalic liquid with an pH > 11. The substance is classified as corrosive (Skin Corr 1B, H314 and Eye Damage 1, H 318). Additionally, titanium tetrakic(dimethylammonium) can only be handled in air-free environments. It is a flammable liquid and extremely unstable (see also chapter 1.2 or 5.1.2 or 13). Within seconds, it reacts violently in contact with moisture or water. The decomposition products are dimethylamine and titanium oxide. Dimethylamine is a highly flammable gas, but dimethylamine is well water soluble, highly basic, and corrosive to skin and eyes. In an acute inhalation toxicity study with dimethylamine (Steinhagen et al.), severe corrosive and necrotic effects were observed on eyes, skin, and mucous nasal membranes
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
