Registration Dossier
Registration Dossier
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EC number: 221-904-3 | CAS number: 3275-24-9
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2020-02-12
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Guideline:
- other: decompositon of TDMAT in water was detected by NMR method
- Principles of method if other than guideline:
- The decomposition of TDMAT in water within minutes was detected by NMR method
- GLP compliance:
- no
- Specific details on test material used for the study:
- purity: 99.5%
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Positive controls:
- no
- Negative controls:
- no
- Transformation products:
- yes
- No.:
- #1
- No.:
- #2
- Details on hydrolysis and appearance of transformation product(s):
- TDMAT disappeared within minutes. After 8 minutes the substance was no more detectable by NMR spectroscopy. Hydrolysis products are dimethylamine and titanium dioxide
The included references from literature confirm these results - Executive summary:
TDMAT disappeared within minutes. After 8 minutes the substance was no more detectable by NMR Spectroscopy. Hydrolysis products are dimethylamine and titanium dioxide. The formation of the degradation products are confirmed by published literature.
Reference
Description of key information
TDMAT disappeared within minutes. After 8 minutes the substance was no more detectable by NMR Spectroscopy. Hydrolysis products are dimethylamine and titanium dioxide. The formation of the degradation products are confirmed by published literature.
Key value for chemical safety assessment
Additional information
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