Registration Dossier
Registration Dossier
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EC number: 220-103-6 | CAS number: 2628-17-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in chemico
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 442C (In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA))
- Deviations:
- no
- GLP compliance:
- yes
- Type of study:
- direct peptide reactivity assay (DPRA)
Test material
- Reference substance name:
- p-vinylphenol
- EC Number:
- 220-103-6
- EC Name:
- p-vinylphenol
- Cas Number:
- 2628-17-3
- Molecular formula:
- C8H8O
- IUPAC Name:
- p-vinylphenol
- Test material form:
- solid: particulate/powder
Constituent 1
In chemico test system
- Details on the study design:
- Study design was as required under OECD442C.
Results and discussion
In vitro / in chemico
Results
- Key result
- Run / experiment:
- other: DPRA
- Parameter:
- other: DPRA
- Value:
- 0
- Vehicle controls validity:
- valid
- Negative controls validity:
- valid
- Positive controls validity:
- valid
- Other effects / acceptance of results:
- substance polymerised during the study
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Due to the polymerisation of p-vinyl phenol during the study it was not possible to complete the study and hence no classification for skin sensitisation can be determined.
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