Registration Dossier
Registration Dossier
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EC number: 215-716-0 | CAS number: 1345-07-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In this 72-h algal growth inhibition test with Pseudokirchneriella subcapitata, the obtained results showed that the test item Dibismuth trisulfide had no toxic effect at aquatic saturation on the algae.
Accordingly, the EC10, EC50 and the LOEC values based on growth rate and yield were determined to be higher than the solubility level of the test item in the test medium which corresponds to a nominal value of > 100 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 100 mg/L
Additional information
Key 001
The results of the statistical evaluation showed that the 0-72 h average specific growth rate and yield at the treatment group (100% v/v saturated solution, equivalent to 100 mg/L nominal concentration) was not statistically significantly different from the untreated control. Accordingly, the No Observed Effect Concentration (NOEC) was determined as the saturation concentration.
Because the test item had no significant effect on the growth of algae, therefore statistical analysis was not performed to determine the EC values.
The 72-h EC50 values based on growth rate and yield were determined to be higher than saturation.
Even the supersaturated test item concentration of 1000 mg/L in the pre-experiments didn’t show any toxic effects.
In this 72-h algal growth inhibition test with Pseudokirchneriella subcapitata, the obtained results showed that the test item Dibismuth trisulfide had no toxic effect at aquatic saturation on the algae.
Accordingly, the EC10, EC50 and the LOEC values based on growth rate and yield were determined to be higher than the solubility level of the test item in the test medium which corresponds to a nominal value of > 100 mg/L.
Waiver
Dibismuth trisulfide is insoluble (see IUCLID section 4.8 Water solubility) and revealed no acute environmental hazard, thus, the long-term testing was waived in accordance with column 2 REACH Regulation (EC) No 1907/2006 Annex IX section 9.1.
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