Registration Dossier
Registration Dossier
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EC number: 215-716-0 | CAS number: 1345-07-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on the results of this study, the test item dibismuth trisulfide had no toxic effect at aquatic saturation on Daphnia magna; the LC50 results and the LOEC are higher than the solubility level of the test item in the test medium which corresponds to a nominal test item concentration of > 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
The acute toxicity of dibismuth trisulfide to daphnia magna was determined in a 48-hour immobilisation test according to OECD guideline 202.
A limit test was performed in which, the test animals were exposed to aqueous test media containing the test item for 48 hours at the limit of its solubility in the test medium (i.e. saturation) plus a control in order to demonstrate that the test item has no influence on the mobility of Daphnia up to at least the saturation concentration. There was no immobilisation in twenty daphnids exposed to either test item treated or control group. In addition to immobility, no abnormal behaviour or appearance of test animals was detected.
Accordingly, the 48-h NOEC was determined as the saturation concentration (i.e. 100% v/v saturated solution, equivalent to 100 mg/L nominal concentration) and the LOEC and the LC50 values were determined to be higher than saturation.
Even the supersaturated test item concentration of 1000 mg/L in the pre-experiments did not show any toxic effects.
Based on the results of this study, the test item dibismuth trisulfide had no toxic effect at aquatic saturation on daphnia magna; the LC50 results and the LOEC are higher than the solubility level of the test item in the test medium which corresponds to a nominal test item concentration of > 100 mg/L.
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