Registration Dossier
Registration Dossier
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EC number: 225-059-1 | CAS number: 4635-59-0
Endpoint summary
Administrative data
Description of key information
Additional information
Phototransformation in air
Parent compound 4 -chlorobutyryl chloride and hydrolysis product 4 -chlorobutyric acid:
After evaporation or exposure to air, the substance will be slowly degraded by photochemical processes.
This estimation refers to dry air. In mist, rain, droplets and aerosols, hydrolysis will be the major fate process of the acid chloride due to the short half-life in aqueous solution. Therefore this estimate may be of low relevance.
Hydrolysis
Parent compound 4 -chlorobutyryl chloride is determined to hydrolyse rapidly to 4 -chlorobutyric acid and HCl.
Hydrolysis product: In accordance with column 2 of REACH Annex VII, the study does not need to be performed if the substance is readily biodegradable or inorganic. 4 -chlorobutyryl chloride hydrolyses rapidly and forms 4 -chlorobutyric acid and HCl. 4 -chlorobutyric acid is readily biodegradable, while HCl is inorganic.
Biodegradation
As the parent compound hydrolyses in water within 10 minutes the assessment of the biodegradability relates to the 4 -chlorobutyric acid. The hydrolysis product turned out to be readily biodegradable.
Bioaccumulation
Parent compound 4 -chlorobutyryl chloride and hydrolysis product 4 -chlorobutyric acid: Significant accumulation in organisms is not to be expected.
However, the assessment of the bioaccumulation potential of the parent compound may be of low relevance due to the rapid hydrolysis of the acid chloride in aqueous solutions.
Adsorption / desorption
Parent compound 4 -chlorobutyryl chloride and hydrolysis product 4 -chlorobutyric acid: Adsorption to solid soil phase is not expected.
However, the assessment of the adsorption potential of the parent compound may be of low relevance due to the rapid hydrolysis of the acid chlorid in aqueous solutions.
Henry's Law constant
Parent compound 4 -chlorobutyryl chloride: From the water surface, the substance will slowly evaporate into the atmosphere.
Hydrolysis product 4 -chlorobutyric acid: From the water surface, the substance will not evaporate into the atmosphere.
However, the assessment of the volatility of the parent compound may be of low relevance due to the rapid hydrolysis of the acid chloride in aqueous solutions.
Distribution modelling
Parent compound 4 -chlorobutyryl chloride: Over time, the substance will preferentially distribute into the compartments water (66.9%) and air
(33.0%). However, the model calculation may be of low relevance as the compound rapidly decomposes in water (t1/2<< 24 h).
Hydrolysis product 4 -chlorobutyric acid: Over time, the substance will preferentially distribute into the water (98.5%).
However, the model does not consider the ionic structure of the molecule at environmentally relevant pH conditions (pH 5 to pH 9; pKa value: 4.35 @ 25 °C). Therefore, the model may underestimate the distribution into water.
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