Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Quality of whole database:
Sufficient to meet data requirements. The two-generation reproductive toxicity study is waived in accordance with Annex IX, 8.7.3 column 1 of the REACH regulation.
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information

The two-generation reproductive toxicity study is waived in accordance with Annex IX, 8.7.3 column 1 of the REACH regulation. The available repeat dose toxicity data indicates no adverse effects on reproductive organs or tissues.

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Quality of whole database:
This study is waived in accordance with Annex XI, section 3.2.(b) of the REACH regulation.
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available
Additional information

The developmental toxicity study is waived in accordance with Annex XI, section 3.2.(b) of the REACH regulation. HMBDA is not incorporated in an article and for all relevant scenarios throughout the life cycle strictly controlled conditions apply.

Justification for classification or non-classification

There is no evidence from the available toxicology studies to indicate that HMBDA is toxic to reproduction and is therefore not classified.

Additional information