Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 223-861-6 | CAS number: 4098-71-9
Endpoint summary
Administrative data
Description of key information
Additional information
The registered substance exhibits a dissipation time in water less than the cut-off value of 12 h and is therefore considered as hydrolytically unstable. Upon contact with water, the diisocyanate groups of IPDI react by forming amines and CO2. The amines (i.e. isophorone diamine) react further with unreacted diisocyanate groups of IPDI resulting in oligo- and subsequently polyurea components.
The log Kow of the hydrolysis product isophorone diamine (IPDA, CAS 2855-13-2) was determined according to OECD 107 as 0.99 indicating a low potential for bioaccumulation. Moreover, a BCF value of 3.16 was calculated by QSAR (BCFWin v2.14 as integrated in EPIWIN v3.10) that also indicates a low potential for bioaccumulation. Beside IPDA, polyurea components are formed that are due to their molecular size, low mobility and high log Kow not bioavailable (low potential to cross biological membranes).
Hence, the potential for bioaccumulation for IPDI and its hydrolysis products (IPDA and polyurea) can be considered as low.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
