Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Methyl acrylate
  • IUPAC name: methyl prop-2-enoate
  • Other names
EC / List no.:
202-500-6
CAS no.:
96-33-3
Index number:
607-034-00-0
Molecular formula:
C4H6O2
SMILES:
COC(=O)C=C
InChI:
InChI=1S/C4H6O2/c1-3-4(5)6-2/h3H,1H2,2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
19
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a highly flammable liquid and vapour, is harmful if swallowed, is harmful in contact with skin, causes serious eye irritation, is harmful if inhaled, causes skin irritation, may cause an allergic skin reaction and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic if inhaled and is harmful to aquatic life with long lasting effects.

Breakdown of all 700 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
Acute Tox. 4 H312 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Acute Tox. 3 H331
Acute Tox. 4 H332 Harmonised Classification
Aquatic Chronic 3 H412
Skin Sens. 1B H317
Acute Tox. 3 H301
Aquatic Chronic 2 H411
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 52 active registrations under REACH, 2 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 10 000 - 100 000 tonnes per year.

This substance is used in articles, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, as processing aid, manufacturing of the substance and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: polymers. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals and plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers, laboratory work, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; keep container tightly closed; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: In case of fire: Use (measures specified by manufacturer/supplier) for extinction.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M Deutschland GmbH, Carl-Schurz-Strasse 1 41453 Neuss Germany
  • 3M France SAS, 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France
  • ARKEMA FRANCE, 420 rue d'Estienne d'Orves 92700 COLOMBES France
  • Avery Dennison Materials Europe BV, Willem Einthovenstraat 11 2342 BH Oegstgeest Zuid-Holland Netherlands
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • BASF Antwerpen N.V., Haven 725, Scheldelaan 600 2040 Antwerpen 4 Antwerpen Belgium
  • BCS Only Representative Services Ltd, Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland
  • BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemra GmbH, Max-Planck-Strasse 12 54296 Trier Germany
  • Chemservice S.A. (F7R3), 5, an de Laengten 6776 Grevenmacher Luxembourg
  • COVANCE CRS SA 104, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. - OR2, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • ECEM, Hogehilweg 18 1101CD Amsterdam Noord Holland Netherlands
  • Elementis UK Ltd., Caroline House 55 - 57 High Holborn WC1V 6DX London United Kingdom
  • ERM_GmbH_OR13_KM, Siemenstrasse 9. 63263 Neu Isenburg Hessen Germany
  • Gazprom Marketing & Trading France27, 68 avenue des Champs Elysées 75008 PARIS France
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Intertek Deutschland GmbH 16, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • JACOBI CARBONS AB, Slojdaregatan 1 393 53 Kalmar Sweden
  • Jindal Films Europe Virton sprl, Zoning Industriel de Latour 6761 VIRTON Belgium
  • Kemira Oyj, Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • LG Chem Europe GmbH, Lyoner str 15, Atricom C6, D-60528 Frankfurt am Main Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Limited, The Knowle, Nether Lane Hazelwwod DE56 4AN Derby Derbyshire United Kingdom
  • Lucite OR MCC Nantong China, Wilton Centre Wilton TS10 4RF Redcar Cleveland United Kingdom
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden
  • Performance Materials Ibérica, S.L.U., Av. Diagonal Num. 571 08029 Barcelona Spain
  • Purolite Ltd., Llantrisant Business Park CF72 8LF Llantrisant Wales United Kingdom
  • Resindion S.r.l., Via Roma, 55 20082 Binasco Milano Italy
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Netherlands
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • Specialty Electronic Materials Netherlands B.V., Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Specialty Electronic Materials Netherlands B.V. OR-5, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Synthomer a.s., Tovární 2093 356 01 Sokolov Czech Republic
  • TOYO INK EUROPE SPECIALTY CHEMICALS, Boulevard Dambourney BP4 76350 Oissel France
  • Tyco Electronics EC Trutnov s.r.o., Komenského 821 Trutnov 54183 Trutnov Czech Republic Czech Republic
  • TÜV SÜD Iberia S.A.U. (052), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • TÜV SÜD Iberia S.A.U. (053), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • [Confidential], [Confidential]
  • Arcerion GmbH, Gabrielenstr. 15 80636 Muenchen Germany
  • Baltic International Trading OU, 5 Ryavala 10143 Tallinn Estonia
  • Henkel AG & Co. KGaA, Henkelstrasse 67 40191 Duesseldorf North-Rhine Westfalia Germany
  • Henkel Belgium Operations N.V., Havenlaan 16 1080 Brussels Belgium
  • Henkel Italia Operations S.r.L., Via Amoretti 78 20157 Mailand Italy
  • Intertek Deutschland GmbH ITCI, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • [Confidential], [Confidential]

Other names

  • -
  • 2-Propenoic acid, methyl ester
  • Methyl 2-propenoate
  • METHYL ACRYLATE
  • Methyl acrylate (MA)
  • Methyl Acrylate (stabilized with MEHQ)
  • Methyl acrylate(MA)
  • methyl acrylate/methyl propenoate
  • Methyl prop-2-enoate
  • Methyl propenoate
  • Methylacrylat
  • Methyl_Acrylate
  • Methyl acrylate
  • methyl propenoate
  • 2-Propenoic acid methyl ester
  • 2-Propenoic acid, methyl ester
  • 2-Propenoic acid, methyl ester (9CI)
  • ACRYLIC ACID METHYL ESTER
  • Acrylic acid methyl ester (6CI, 8CI)
  • MA
  • Methoxycarbonylethylene
  • METHYL 2-PROPENOATE
  • Methyl Acrylate
  • Methyl acrylate; Acrylic acid methyl ester
  • METHYL ACRYLIC
  • Methyl acrylic ester
  • Methyl Acylate Monomer
  • Methyl prop-2-enoate
  • Methyl propenoate
  • Methyl-2-propenate
  • METHYL-2-PROPENOATE
  • Methylacrylat
  • Methylpropenoat
  • Propenoic acid methyl ester
  • Propeonic acid methyl ester, Methyl-2-propenoate, acrylic acid methyl ester

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Liquid (50%), Other (50%) [2]
C Odour
Pungent (50%), Other (50%) [2]
C Substance type
Organic (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-75.6 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-76.5 °C

Boiling point

Study results
  • 3 studies submitted
  • 1 study processed
R Boiling point
80.1 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
80.1 °C

Density

Study results
  • 4 studies submitted
  • 1 study processed
R Density
0.954 g/cm³ @ 20 °C [1]
R Relative density
0.95 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
950

Vapour pressure

Study results
  • 5 studies submitted
  • 1 study processed
R Vapour pressure
90 - 150 hPa @ 20.2 - 30.8 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 1 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
90 hPa @ 20 °C

Partition coefficient

Study results
  • 8 studies submitted
  • 1 study processed
R Log Pow
0.739 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
0.739 @ 25 °C

Water solubility

Study results
  • 5 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
60 g/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
60 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 5 studies submitted
  • 1 study processed
R Flash point
-2.8 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
-2.75 °C

Auto flammability

Study results
  • 3 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
468 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
468 °C

Flammability

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 3
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.472 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.472 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 3 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
40.9 h [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Biodegradation in water - screening tests

Study results
  • 7 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 4
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1 3 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
6.4

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
9.37 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
9.37 Pa.m³.mol-1 @ 20 °C

Distribution modelling

Study results
  • 2 studies submitted
  • 1 study processed
% Distribution in Media:
R Air 81.9 % [1]
R Water 18 % [1]
R Soil 0.01 % [1]
R Sediment 0.01 % [1]
R Suspended sediment 0 % [1]
R Biota 0 % [1]
R Aerosol 0 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 2.72 µg/L (1)
Intermittent releases (freshwater) 11 µg/L (1)
Marine water 270 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 11.5 µg/kg sediment dw (1)
Sediment (marine water) 11.5 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 1 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning 1.1 mg/kg food (1)

Short–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 1.1 - 3.4 mg/L [2]
LC0 (4 days) 890 - 2 800 µg/L [2]
NOEC (4 days) 890 - 2 800 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 2.6 mg/L [1]
LC50 (4 days) 1.6 mg/L [1]
EC0 (48 h) 880 µg/L [1]
LC0 (4 days) 990 µg/L [1]
EC100 (48 h) 6.4 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
2.6 mg/L
EC50 / LC50 for marine invertebrates
1.6 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 5 studies submitted
  • 5 studies processed
P/RResults
NOEC (21 days) 136 - 457 µg/L [8]
LOEC (21 days) 450 - 1 226 µg/L [8]
EC50 (21 days) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 3 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
136 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 2.02 - 3.55 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
3.55 mg/L

Toxicity to aquatic plants other than algae

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to microorganisms

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
EC10 (72 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
EC50 (28 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 18 mg/m³ irritation (respiratory tract)
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: (DNEL) 490 µg/cm² sensitisation (skin)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 2.1 mg/m³ irritation (respiratory tract)
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 490 µg/cm² sensitisation (skin)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 15 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 4
Supporting study 7
Weight of evidence
Other 4
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 9 studies submitted
  • 1 study processed
P/RResults
LD50 768 mg/kg bw (rat) [1]
M/CInterpretations of results
Harmful [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 8
Data waiving
no waivers
inhalation
  • 17 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 10.832 mg/L air (rat) [1]

inhalation
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other 12
Data waiving
no waivers
dermal
  • 5 studies submitted
  • 1 study processed
P/RResults
LD50 1 250 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Harmful [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
other routes
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 6
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 3
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 12 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 10
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Study data: inhalation
  • 15 studies submitted
  • 1 study processed
P/RResults
NOAEC (rat): 82 mg/m³ air [1]
LOAEC (rat): 440 mg/m³ air [1]

Study data: inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 14
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study
Supporting study 4
Weight of evidence 7
Other 5
Data waiving
no waivers
Study data: in vivo
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant