Registration Dossier
Registration Dossier
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EC number: 201-170-0 | CAS number: 79-03-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: With high probability acutely not harmful to fish.
Hydrolysis product: With high probability acutely not harmful to fish.
Hydrolysis product HCl: Acutely toxic for fish (pH-dependent).
Key value for chemical safety assessment
Additional information
Parent compound propionyl chloride:
The toxicity of propionyl chloride (CAS 79 -03 -8) to the test organism Danio rerio was tested according to OECD 203 (Fish, acute Toxicity Test). The 96 -h LC50 was determined to be 301 mg/L (measured, not neutralized; BASF AG, 1999/2011; report no. 17F0561/965165). No fish died in a neutralised sample of 464 mg/L (nominal; ca. 100% recovery) which was tested in parallel.
Based on the reported test results the substance is with high probability acutely not harmful to fish.
Hydrolysis product propionic acid:
No reliable data is available for propionic acid (CAS 79 -09 -4). Regarding the rapid hydrolysis of propionyl chloride to propionic acid and HCl, the assessment of propionic acid will be based on the result for the parent substance. Therefore, propionic acid is with high probability not acutely harmful to fish.
Hydrolysis product hydrochloric acid (HCl):
HCl was tested in a semi-static acute toxicity test according to OECD 203 with Cyprinus carpio. The 96-h LC50 was 4.92 mg/L (acid equivalent to pH 4.3; OECD, 2002).
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