Registration Dossier
Registration Dossier
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EC number: 217-682-2 | CAS number: 1929-82-4
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- no data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Peer reviewed secondary source with dose decriptor provided only.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Test Item: A scientific advisory group review of the mode of action and carcinogenicity in B6C3F1 mice
- Author:
- B.L. Yano , J.F. Hardisty, J.C. Seely, B.E. Butterworth, E.E. McConnell, J.A. Swenberg, G.M. Williams, K.E. Stebbins, B.B. Golllapudi, D.L. Eisenbrandt
- Year:
- 2 008
- Bibliographic source:
- Regulatory Toxicology and Pharmacology 51 (2008) 53–65
- Reference Type:
- other: study report as cited in secondary source
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
- Principles of method if other than guideline:
- Secondary literature source no data about the method was available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Nitrapyrin
- EC Number:
- 217-682-2
- EC Name:
- Nitrapyrin
- Cas Number:
- 1929-82-4
- Molecular formula:
- C6H3Cl4N
- IUPAC Name:
- 2-chloro-6-(trichloromethyl)pyridine
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- not specified
- Controls:
- not specified
- Details on study design:
- no data available
Results and discussion
In vivo
Results
- Irritation parameter:
- other: no data available
- Basis:
- other: no data available
- Time point:
- other: no data available
- Reversibility:
- not specified
- Remarks on result:
- other: The test item caused transient eye irritation in New Zealand White rabbits
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
