Registration Dossier

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

In accordance with the General Rules for Adaptation of the Standard Testing Regime (Annexes VII-X) as stated in REACH Annex XI, this endpoint can be waived as the substances are not expected to undergo hydrolysis in the environment due to a lack of hydrolysable functional groups and therefore testing does not appear scientifically necessary. 

Key value for chemical safety assessment

Additional information

Hydrolysis is the reaction in which a water molecule or hydroxide ion substitutes for another atom or group of atoms present in a chemical resulting in a structural change of that chemical. Potentially hydrolysable groups include alkyl halides, amides, carbamates, carboxylic acid esters and lactones, epoxides, phosphate esters, and sulfonic acid esters. The lack of a suitable leaving group renders compounds resistant to hydrolysis.

The chemical constituents that comprise 2 -methylbutane consist entirely of carbon and hydrogen and do not contain hydrolyzable groups. As such, they have a very low potential to hydrolyze. Therefore, this degradative process will not contribute to their removal from the environment.