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Physical & Chemical properties

Water solubility

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Description of key information

The water solubility is 0.0485 g/l at 25°C for 2-methylbutane (Lide 2008). 

Key value for chemical safety assessment

Water solubility:
0.049 g/L

Additional information

The water solubility of 2 -methylbutane is taken from the CRC Handbook (Lide 2008). The CRC Handbook is considered a reliable, peer-reviewed handbook and suitable for use as the key study for this endpoint. Other values reported by McAuliffe (1966) are in agreement with the value reported in the CRC Handbook of 0.0485 g/l at 25°C. Therefore this value will be used as the key study value.

McAuliffe (1966) is well documented and meets basic scientific principles. The solubilities of 65 hydrocarbons in water were measured, at room temperature, by the direct injection of hydrocarbon-saturated water into a gas chromatograph. The concentration of hydrocarbon was determined by measuring the area under the chromatogram peak. It is unclear what effect impurities might have had on the result and how the authors accounted for them in determining the solubility value. The study predates implementation of GLP and development of standard guidelines but otherwise acceptable for assessment and has been classified as reliable with restrictions.