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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Bis(2,3-epoxypropyl)cyclohexane-1,2 -dicarboxylate was found to be moderately toxic to fish (fathead minnow) with a 96h LC50 of 17.0 mg/L in an OECD 203 guideline study. The 96h mortality threshold concentration was 12 mg/L and the no observed concentration (NOEC) was 7.0 mg/L. The result was confirmed in a second study performed in Carp which showed an 96h LC50 of 35 mg/L.

The substance was slightly toxic to Daphnia magna when tested according to OECD 202. The 48h LC50 value and 95% confidence interval were calculated based on nominal exposure concentrations and were determined to be 71.6 (65.8-78.8) mg/L. The NOEC was 36 mg/L.

The substance was reported to have slight toxicity to the green algae Pseudokirchnerella subcapitata, with a 72-h ErC50 value for growth rate just above 56 mg/L (TWA) in an OECD guideline study (Test No. 201).

The substance was reported to have no toxicity to microorganisms (Pseudomonas Putida), with a 18-h IC50 value for growth inhibition greater than 10000 mg/L (nominal) in an DIN 38412, part 8, study.