Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

The Nicotinamide toxicokinetic assessment is based on a weight of evidence approach. Following references were included: 
- EC Scientific Committee on Food (2002) Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Levels of Nicotinic acid and Nicotinamide (Niacin)
- EFSA Panel on Additives and Products or Substances used in Animal Feed (2012) Scientific Opinion on the safety and efficacy of Niacin (Nicotinic acid and Nicotinamide) as a feed additive for all animal species. EFSA Journal 10(7): 2781.
- FDA 21CFR184.1535 (1979)
- OECD SIDS Report 3-Pyridinecarboxamide (Nicotinamide, 2002)
- UK Food Standards Agency Expert Group on Vitamins and Minerals (2003) Safe Upper Levels for Vitamins and Minerals.

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information