Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-857-4 | CAS number: 544-01-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The test was conducted in accordance with GLP and an international test guideline (OECD 201). The test species was Pseudokirchneriella subcapitata and the 72h-EC50 and NOEC values of >4.36 and 1.15 mg/L were based on growth rate as required by the ECHA endpoint specific guidance.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 4.36 mg/L
- EC10 or NOEC for freshwater algae:
- 1.15 mg/L
Additional information
A GLP compliant OECD 201 algal inhibition assay (Pseudokirchneriella subcapitata) with diisopentyl ether was conducted with confirmation of test solution concentrations at 0 and 72 hours. The test was conducted at nominal concentrations of Control, solvent control, 5.0, 7.1, 10.0, 14.1 and 20.0 mg/L the concentration range was based on the results of a range finding test.
There were 3 replicate test vessels per treatment, each initially inoculated with 5,000 algal cells/mL. Exposure concentrations were verified analytically at the start and end of the test. Mean measured concentrations were used to calculate the inhibition concentrations.
The EbC50 (72 h) and ErC50 (72 h) endpoints both exceeded 4.36 mg/L diisopentyl ether, based on the mean measured exposure concentration. This concentration is the maximum possible concentration of the test solution preparation (20 mg/L, average of measurement value: 4.36 mg/L).
Based on the absence of statistically significant effects on algal growth at all of the applied treatments, compared to the untreated control, the NOEC was 1.15 mg/L (mean measured).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
