Registration Dossier
Registration Dossier
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EC number: 223-810-8 | CAS number: 4083-64-1
Vapour pressure
Administrative data
Link to relevant study record(s)
Description of key information
The vapour pressure of p-toluenesulfonyl isocyanate was found to be 0.025 Pa at 25ºC.
The vapour pressure of p-toluenesulfonamide (PTSA), the decomposition product of PTSI, was also determined for risk assessment purposes and was found to be < 0.000286 Pa at 20ºC.
Key value for chemical safety assessment
- Vapour pressure:
- 0.025 Pa
- at the temperature of:
- 25 °C
Additional information
The vapour pressure of p-Toluenesulfonyl Isocyanate was determined in an in-house, non GLP study using the boiling point method. The boiling temperature of the substance was determined at six different pressures. Based on linear regression the vapour pressure at 25°C was predicted to be 2.47E-7 Atm. or 0.000188 mm Hg (equivalent to 0.025 Pa).
A value for vapour pressure of the metabolite p-toluenesulfonamide (PTSA, CAS 70-55-3) is also required for risk assessment. The vapour pressure for PTSA, obtained in a non-GLP test according to ASTM E1782-08 using Differential Scanning Calorimetry, is < 0.000286 Pa at 20ºC.
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