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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Additional information

Based on its extreme reactivity with moisture/water, p-toluenesulfonyl isocyanate is classified with R14 - Reacts violently with water. Further classification for physical chemical hazards is not required according to the criteria of the Dangerous Substances Directive 67/548/EEC.

Based on its extreme reactivity with moisture/water, p-toluenesulfonyl isocyanate should be assigned the statement EUH014 - Reacts violently with water. Further classification for physical chemical hazards is not required according to the criteria of CLP, Regulation 1272/2008/EC.

The substance is a clear liquid with an acrid odour at room temperature.

The substance has a melting point of -2.37ºC.

The substance decomposes before boiling.

The substance has a relative density of 1.295 at 20ºC.

The vapour pressure of the substance was found to be 0.025 Pa at 25°C. The vapour pressure of p-toluenesulfonamide (PTSA), the decomposition product of PTSI, was also determined for risk assessment purposes and was found to be < 0.000286 Pa at 20ºC.

The water solubility of p-toluenesulfonyl isocyanate could not be determined experimentally due to its instability in contact with water. Instead, for risk assessment purposes the value for its metabolite p-toluenesulfonamide is used: 3.1 g/L 20ºC.

The partition coefficient of p-toluenesulfonyl isocyanate could not be determined experimentally due to its instability in contact with water. Instead, for risk assessment purposes the value for its metabolite p-toluenesulfonamide is used: 0.6 at 30ºC.

The substance has a flash point of 146ºC.

The substance has an autoflammability temperature of 551ºC.

The dynamic viscosity was found to be 5.155 mPa.s at 20ºC.

The substance is not highly flammable.

The substance is not explosive.

The substance is not an oxidising substance.