Registration Dossier
Registration Dossier
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EC number: 268-092-7 | CAS number: 68002-78-8 This substance is identified by SDA Substance Name: C16-C18 and C18 unsaturated trialkyl carboxylic acid trimethylolpropane triester and SDA Reporting Number: 11-015-00.
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
NOEC = 1000 mg/kg for Eisenia fetida (OECD 222)
Key value for chemical safety assessment
Additional information
Experimental data on the toxicity of Fatty acids, C16-18 and C18-unsatd., triesters with trimethylolpropane (CAS 68002-78-8) to soil macororganisms are not available. The evaluation therefore refers to the structural analogue category member 2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis (isooctadecanoate) (CAS 68541-50-4) as part of a read across approach. This is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the analogue justification section 13.
The long-term toxicity of the read-across substance2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis (isooctadecanoate) (CAS 68541-50-4)was tested according to OECD guideline 222. The test was conducted with artificial soil that was mixed with the test substance. Earthworms of the species Eisenia fetida were exposed to the test substance for 28 days and then removed from the test substrate. The survival rate and growth (body weight) of the specimen were determined. After another 28 days the hatched juveniles were collected from the test substrate and the reproduction rate was recorded. Mortality or a decrease in body weight of the adult earthworms was not observed. Thus a NOEC of 1000 mg/kg soil based on mortality and a NOEC ≥ 1000 mg/kg soil based on the reproduction rate was determined.
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