Registration Dossier
Registration Dossier
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EC number: 606-947-1 | CAS number: 221640-21-7
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 831 g/L
- Temp.:
- 20 °C
- pH:
- 4 - 5
- Remarks on result:
- other: mean value of three results
- Details on results:
- The main test was performed with the maximum concentration of the test item in water which could be stirred.
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- can be considered as very soluble with a water solubility of 831 g/L at 20 °C. The pH value of the solutions was determined to be between 4 and 5. - Executive summary:
The water solubility of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was determined with the flask method at 20 °C and HPLC-analysis according to OECD TG 105. 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- can be considered as very soluble with a water solubility of 831 g/L at 20 °C. The pH value of the solutions was determined to be between 4 and 5.
Reference
Description of key information
1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- can be considered as very soluble with a water solubility of 831 g/L at 20 °C. The pH value of the saturated water solution was determined to be between 4 and 5.
Key value for chemical safety assessment
- Water solubility:
- 831 g/L
- at the temperature of:
- 20 °C
Additional information
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