Registration Dossier
Registration Dossier
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EC number: 204-493-5 | CAS number: 121-69-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : BX4725000
- Author:
- U.S. Environmental Protection Agency
- Year:
- 2 012
- Bibliographic source:
- RTECS ;HPV300 U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Monocyclic Aromatic Amines (MAA) Category.pdf http://www.epa.gov/HPV/pubs/summaries/aroamin/c13310tc.htm Volume(issue)/page/year: -,-,2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- standard acute method
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- N,N-dimethylaniline
- EC Number:
- 204-493-5
- EC Name:
- N,N-dimethylaniline
- Cas Number:
- 121-69-7
- Molecular formula:
- C8H11N
- IUPAC Name:
- N,N-dimethylaniline
- Details on test material:
- - Name of test material (as cited in study report): N,N-dimethylaniline
- Substance type: Organic
- Physical state: liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 4 h
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LCLo
- Effect level:
- 250 mg/m³ air
- Based on:
- test mat.
- Exp. duration:
- 4 h
Applicant's summary and conclusion
- Interpretation of results:
- moderately toxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Lowest lethal concentration (LCLo) by inhalation route of N,N-dimethylaniline was found to be 250 mg/m3 indicating that the chemical is moderately toxic.
- Executive summary:
Lowest lethal concentration (LCLo) by inhalation route of N,N-dimethylaniline was found to be 250 mg/m3 indicating that the chemical is moderately toxic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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