Registration Dossier
Registration Dossier
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EC number: 204-493-5 | CAS number: 121-69-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The effective concentration (EC50) value for N, N-dimethylaniline in Tetrahymena pyriformis in a 24 hr study were found to be 110 mg/L on the basis of effect on population growth rate.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 110 mg/L
Additional information
Based on studies of target substanceN,N-dimethylanilinereviewed for toxicity to microorganism from reliable sources having Klimisch rating 2 considering weight of evidence approach
The summary of the results are presented below
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1. |
EC50 |
110 mg/l |
growth inhibition |
24 hrs |
Tetrahymena pyriformis |
Publication |
2. |
EC50 |
59.4882 mg/l |
growth inhibition |
46 hrs |
Tetrahymena pyriformis |
Publication |
3. |
EC50 |
13.6 mg/L |
reduction in light emission |
30 min |
Photobacterium phosphoreum |
Publication |
Based on the results summarized in above table for the target substanceN,N-dimethylanilinethe endpoint values of microorganism (Tetrahymena pyriformis and Photobacterium phosphoreum), varies from 13.6 mg/L to 110 mg/l.
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