Rapal 01, Paval, Serox, Argalum

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Qualifier:

according to guideline

Guideline:

ISO 13320 (Particle size analysis - Laser diffraction methods)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

Laser scattering/diffraction

Type of distribution:

volumetric distribution

Specific details on test material used for the study:

The test item was mixed prior to the study by the test facility in equal parts from the following three subsamples:

Subsample 1:
Supplier: Befesa Aluminio S.L
Carreta Luncaha- Asúa 13
48950 Erandio (Vizcaya), Spain
Batch No.: Paval Nov 2020
Appearance: Grey solid
Storage conditions: Ambient temperature (10 °C to 30 °C)
Expiry date: November 19, 2021

Subsample 2:
Supplier: RAFFMETAL SPA
Via Malpaga 82
25070 Casto (BS), Italy
Batch No.: Rapal01 Nov 2020
Appearance: Grey solid
Storage conditions: Ambient temperature (10 °C to 30 °C)
Expiry date: December 16, 2021

Subsample 3:
Supplier: Intals SPA
Via Schievano 7
20100 Milano (MI), Italy
Batch No.: Argalum Dec 2020
Appearance: Grey solid
Storage conditions: Ambient temperature (10 °C to 30 °C)
Expiry date: January 11, 2022

Percentile:

D90

Mean:

1 530 µm

St. dev.:

21.4

Percentile:

D10

Mean:

10.4 µm

St. dev.:

0.07

Percentile:

D50

Mean:

814.6 µm

St. dev.:

9.9

Prior to the measurement the test item was sieved with a mesh size of 1000 µm. 96.2 % (w/w) of the test item passed the sieve and only this fraction was measured with laser diffraction.

The particle size distribution of the test item Aluminium, magnesium and silicon oxides and hydroxides from refinement of aluminium salt slag residues was measured with laser diffraction. Two test series of three measurements each were performed.

The median particle size L₅₀ (D (v, 0.5): 50 % of particle volume with lower particle diameter) deduced from these distributions were:

1^st test series:  L₅₀ = 799.5 µm; 2^nd test series: L₅₀ = 829.8 µm

The average of the median particle size L₅₀ was: L₅₀ = 814.6 µm

The particle size L₁₀ (D (v, 0.1): 10 % of particle volume with lower particle diameter) deduced from these distributions were:

1^st test series:  L₁₀ = 10.3 µm; 2^nd test series: L₁₀ = 10.4 µm

The average of the particle size L₁₀ was: L₁₀ = 10.4 µm

The particle size L₉₀ (D (v, 0.9): 90 % of particle volume with lower particle diameter) deduced from these distributions were:

1^st test series:  L₉₀ = 1523 µm; 2^nd test series: L₉₀ = 1537 µm

The average of the particle size L₉₀ was: L₉₀ = 1530 µm

Maxima were observed at approximately 200 µm and approximately 1000 µm. Additionally, a shoulder was observed at approximately 8 µm.

Conclusions:

The median particle size L50 of the test item deduced from the particle size distributions was 814.6 µm.
The particle size L10 of the test item deduced from the particle size distributions was 10.4 µm.
The particle size L90 of the test item deduced from the particle size distributions was 1530 µm.

Executive summary:

Winkler (2021) is a GLP-compliant study following OECD guideline 110. It is reliable without restrictions and can be used as a key study for this endpoint. Particle size distribution was determined using laser diffraction and taken into account for classification (bioavailability).

 

 

 

 

 

 

Description of key information

The median particle size L50 of the test item deduced from the particle size distributions was 814.6 µm.
The particle size L10 of the test item deduced from the particle size distributions was 10.4 µm.
The particle size L90 of the test item deduced from the particle size distributions was 1530 µm.