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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-07-24 to 2018-09-14
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
2014
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
flask method
Key result
Water solubility:
76.4 g/L
Conc. based on:
test mat.
Incubation duration:
> 24 - <= 72 h
Temp.:
20 °C
pH:
3.1
Remarks on result:
other: No Tyndall-effect was observed for any of the centrifuged samples.

Validity Criteria

The study was performed based on GECD Guideline 105 for Testing of Chemicals (1995) and Council Regulation (EC) No. 260/2014, Method A.6.

The validity criteria were fulfilled:

- The concentration measured at each sampling time did not differ for more than 15%.

- Temperatures were kept constant within ± 0.5 °C.

Conclusions:
The solubility of the test item was determined at 20 ± 0.5°C to be 76.4 g/L (pH 3.1) for the samples with pre-incubation times of 24, 48 and 72 h.

Description of key information

The solubility of 2H-Isoindole-2 -ethanesulfonic acid, 1,3 -dihydro-1,3 -dioxo-, potassium salt (1:1) (TA-1) was determined according to OECD 105 (1995) at 20 ± 0.5°C to be 76.4 g/L (pH 3.1) for the samples with pre-incubation times of 24, 48 and 72 h.

Key value for chemical safety assessment

Water solubility:
76.4 g/L
at the temperature of:
20 °C

Additional information