Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 15 January 2018 to 01 May 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: Off-white powder
- Storage condition of test material: At room temperature
Specific details on test material used for the study:
Decomposition temp.: 300°C

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
< 0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
< 0 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

logνT

log PT

PT
[Pa]

200

0.588981

7.03E-5

-4.15

-0.18

0.66

 

0.544942

6.50E-5

-4.19

-0.22

0.60

210

1.28159

1.53E-4

-3.82

0.25

1.8

 

1.16354

1.39E-4

-3.86

0.20

1.6

220

2.80806

3.35E-4

-3.47

0.69

4.9

 

2.61002

 3.12E-4

-3.51

0.65

4.5

Extrapolation of the curve to 20°C or 25°C resulted in values outside the validated range of the method (4.3E-14 Pa and 1.6E-13 Pa, resp.).

Since the weight loss of the test item at 200°C, 210°C and 220°C was lower than the weight loss of reference substance benzo(ghi)perylene at the same temperatures, it was assumed that the vapour pressure of the substance at 20°C (25°C) is lower than the vapour pressure of benzo(ghi)perylene at 20°C (25°C).

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C and 25°C was determined to be <1.3E-8 Pa and <7.2E-8 Pa, resp.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950. A vapour pressure curve was constructed from 5 reference substances. Extrapolation of the curve to 20°C or 25°C resulted in values below the validated range of the method. As the vapour pressure of the substance at the test temperatures was determined to be lower than that of reference substance benzo(ghi)perylene at the same temperatures, it was assumed that the vapour pressure of the substance at 20°C (25°C) is lower than the vapour pressure of benzo(ghi)perylene at 20°C (25°C). The vapour pressure of the substance at 20°C and 25°C was concluded to be <1.3E-8 Pa and <7.2E-8 Pa, resp.