Trehalose

Flammability

Link to relevant study record(s)

Reference

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

24. May - 07 June 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 160805
- Expiration date of the lot/batch: 05 Aug. 2018
- Purity test date: not stated

RADIOLABELLING INFORMATION (if applicable)
not applicable

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Stability under test conditions: assumed stable
- Solubility and stability of the test substance in the solvent/vehicle: not applicable
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: not applicable

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
none

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Interpretation of results:

not classified based on GHS criteria

Conclusions:

the test item TREHALOSE, ANHYDROUS should be considered as
not highly flammable (for EU regulations)
non-flammable solid (for UN regulations)

Executive summary:

First, a safety test was performed. A small amount of the test item was heated on a magnesia

groove with a gas burner in order to derive safety precautions. The test item melted

into a brown-clear liquid. The liquid burned with orange flame. Black and solid residue was

observed.

In the preliminary screening test following the EU method and UN method, the test item

was heated with the flame of a teclu burner. The test item melted slowly into a brown and

clear liquid. The liquid became solid after cooling down. A brown-clear solid was observed.

No signs of ignition were observed.

Therefore, the test item TREHALOSE, ANHYDROUS should be considered as

not highly flammable (for EU regulations)

non-flammable solid (for UN regulations)

Description of key information

one valid Guideline Study available.

A pre-test is reported indicating Trehalose is not (highly) flammable.

Based on handling experience, pyrophoric properties or flammability in contact with water can be excluded.

Key value for chemical safety assessment

Flammability:

not classified