Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 262-309-9
CAS number: 60580-61-2
fate and toxicity of zinc 5-nitroisophthalate in the environment is most
accurately evaluated by separately assessing the fate of its
constituents zinc and 5-nitroisophthalate.
transformation/dissolution tests according to the OECD Series on Testing
and Assessment Number 29 (2001) with a loading of 1 mg/L, a nearly
complete dissolution was already observed after 24 h resulting in
dissolved Zn concentrations of 247 microg Zn/L at pH 6 and 213 a microg
Zn/L at pH 8 (corresponding to 991 and 853 microg/L zinc
5-nitroisophthalate, respectively). Thus, zinc 5-nitroisophthalate is
soluble and expected to dissociate upon contact with water and to
release zinc cations and nitroisophthalate anions. The respective
dissociation is reversible and the ratio of the salt /dissociated ions
is dependent on the metal-ligand dissociation constant of the salt, the
composition of the solution and its pH.
the assessment of enviromental fate of zinc 5-nitroisophthalate,
read-across to the assessment entities soluble zinc substances and
5-nitroisophthalic acid is applied since the ions of zinc
5-nitroisophthalate determine its environmental fate and toxicity. Since
zinc cations and nitroisophthalate anions behave differently in the
environment, including processes such as stability, degradation,
transport and distribution, a separate assessment of the environmental
fate and toxicity of each assessment entity is performed. Please refer
to the data as submitted for each individual assessment entity.
Aquatic toxicity studies with zinc
5-nitroisophthalate are not available. In the assessment of zinc
5-nitroisophthalate, read-across to the assessment entities soluble zinc
substances and 5-nitroisophthalic acid is applied since the ions of zinc
5-nitroisophthalate determine its fate and toxicity in the environment.
Reliable data available for soluble zinc substances and
5-nitroisophthalate indicate that the moiety of ecotoloxicological
concern are zinc cations. QSAR-based predictions for 5-nitroisophthalate
point to low potential for acute (short-term) and long-term aquatic
toxicity to algae, invertebrates and fish. The aquatic hazard assessment
is based on the most toxic moiety, i.e. the zinc cation, and acute and
chronic ecotoxicity reference values of zinc are recalculated for zinc 5
-nitroisophthalate based on a maximum zinc content of 25.5 %.
Zinc 5 -nitroisophthalate meets based on i)
the acute aquatic ecotoxicity values of 136 µg Zn/L and 413 µg Zn/L for
the zinc ion at pH 8 and pH 6 respectively; ii) the maximum zinc content
of zinc 5-nitroisophthalate of 25.5 %, and iii) the resulting acute
ecotoxicity reference value of 533 µg/L zinc 5-nitroisophthalate at pH 8
as worst case, classification criteria of acute (short-term) aquatic
hazard Category 1 of Regulation (EC) No 1272/2008 with an acute M-Factor
Zinc 5 -nitroisophthalate meets based on i)
the lowest chronic aquatic ecotoxicity reference value observed for the
algae Pseudokircherniella subcapitata (19 µg Zn/L) at neutral pH; ii)
the maximum zinc content of zinc 5-nitroisophthalate of 25.5 %, and iii)
the resulting chronic ecotoxicity reference value of 74.5 µg/L zinc
5-nitroisophthalate as worst case, classification criteria of long-term
aquatic hazard of Regulation (EC) No 1272/2008.
The chronic ecotoxicity reference value of
74.5 µg/L is compared with the criteria for long-term aquatic hazard
classification, taking into account whether the zinc, the only toxic
moiety of concern, is considered rapidly degradable or not.
The concept of “Degradability” was developed
for organic substances and is not applicable to inorganic zinc
substances. As a surrogate approach for assessing “degradability”, the
concept of “removal from the water column” was developed to assess
whether or not a given metal ion would remain present in the water
column upon addition (and thus be able to excert a chronic effect) or
would be rapidly removed from the water column. In this concept, “rapid
removal” (defined as >70% removal within 28 days) is considered as
equivalent to “rapidly degradable”. The rapid removal of zinc from the
water column is documented in the section „Environmental fate“.
Consequently, zinc is considered as equivalent to being ‘rapidly
degradable” in the context of classification for chronic aquatic
Based on the chronic ecotoxicity reference
value of 74.5 µg/l, zinc 5-nitroisophthalate meets classification
criteria of long-term aquatic hazard Category 2 in accordance with Table
4.1.0 (b) (ii) of Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again