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In the assessment of zinc 5-nitroisophthalate, read-across to the assessment entities soluble zinc substances and 5-nitroisophthalic acid is applied since the ions of zinc 5-nitroisophthalate determine its fate and toxicity in the environment. Reliable data available for soluble zinc substances and 5-nitroisophthalate indicate that the moiety of ecotoloxicological concern are zinc cations. QSAR-based predictions for 5-nitroisophthalate point to low toxic potential to aquatic algae, invertebrates and fish.

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