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EC number: 204-527-9 | CAS number: 122-19-0
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From October 17, 2017 to October 17, 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- capillary method
- Remarks:
- in a metal block (siwoloboff method)
- Specific details on test material used for the study:
- Identity: Benzyldimethyl(octadecyl)ammonium chloride
Batch no: 14217
Appearance: White to off white solid
Composition: Benzyldimethyl(octadecyl)ammonium chloride
Content: Cationic activity 97.6%
Expiry date: 06/2019
Storage conditions: Room temperature, in dark, in closed vessel - Key result
- Melting / freezing pt.:
- 63.4 °C
- Atm. press.:
- 101.3 kPa
- Decomposition:
- no
- Conclusions:
- Under the study conditions, the melting point of the test substance was determined to be 63.4°C at 101.3 hPa.
- Executive summary:
A study was conducted to determine the melting point of the substance, C18 ADBAC (active content: 97.6%), using capillary metal block method, according to OECD Guideline 102, EU Method A.1 and EPA OPPTS 830.7200. To determine the melting behaviour (three independent single measurements), the test substance was measured by capillary method between 10°C and 400°C. The samples were heated to 55˚C and the measurement was started at a heating range of 0.5˚C/min until the melting temperature was reached. Under the study conditions, the melting point of the test substance was determined to be 63.4°C at 101.3 hPa (Wannenwetsch, 2017).
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- November 24, 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The melting point range indicate a relatively lower purity
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- capillary method
- Remarks:
- in a liquid bath
- Key result
- Melting / freezing pt.:
- ca. 68 - ca. 132 °C
- Atm. press.:
- ca. 1 atm
- Decomposition:
- no
- Conclusions:
- Under the study conditions, the melting point of the test substance was determined to range from 68-132°C
- Executive summary:
A study was conducted to determine the melting point of the test substance, C18 ADBAC (active: 89.5%), using capillary liquid bath method, according to the OECD Guideline 102, in compliance with GLP. Under the study conditions, the melting point of the test substance was determined to range from 68-132°C at 1 atm pressure (Scymaris, 2017).
Referenceopen allclose all
The melting temperature or range was determined for each sample. Results were reported in degree Celsius.
Measurement results:
| Observation | Sample 1 | Sample 2 | Sample 3 | Mean |
| Start of melting | 63.6˚C | 63.2˚C | 63.4˚C | 63.4˚C (336.6 K) |
| No solid particles, clear liquid | 63.6˚C | 63.2˚C | 63.4˚C | 63.4˚C (336.6 K) |
Melting point results:
Test Substance |
Initial Melting point (°C) |
Final Melting point (°C) |
1014.005 |
69 |
130 |
1014.005 |
69 |
130 |
1014.005 |
65 |
135 |
Average |
68 |
132 |
Standard Deviation |
1.89 |
2.36 |
Relative Standard Deviation (%) |
2.79 |
1.79 |
Description of key information
The melting point of the test substance was determined using the capillary metal block and liquid bath methods, according to the OECD Guideline102, EU Method A.1 and EPA OPPTS 830.7200 (Wannenwetsch, 2017 and Scymaris, 2017).
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 63.4 °C
Additional information
Two studies were available with the test substance:
- Study 1: 63.4°C (Wannenwetsch, 2017)
- Study 2: MP ranged from 68-132°C (Scymaris, 2017)
Overall, both the studies support the physical state of the substance. However, the study with a more defined melting point, indicating a more purer form of the test substance, has been considered as the key study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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