Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 919-276-7 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Modelled data indicate a general lack of concern for aquatic hazard with this substance. The substance is not released into the environment and is used as a site-limited intermediate.
Data source
Reference
- Reference Type:
- other: modelled data
- Title:
- EPISUITE 4.1 Results for F-37
- Author:
- U.S. EPA
- Year:
- 2 018
- Bibliographic source:
- U.S. EPA
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Modelled data using acceptable model.
- GLP compliance:
- no
Test material
- Reference substance name:
- n-phenyl n-acetoacetyl glycine ethyl ester
- IUPAC Name:
- n-phenyl n-acetoacetyl glycine ethyl ester
- Test material form:
- liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Total exposure duration:
- 48 h
Test conditions
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- >= 379.384 - <= 944.092 mg/L
- Nominal / measured:
- not specified
- Basis for effect:
- not specified
- Remarks:
- modelled data
- Remarks on result:
- not measured/tested
- Remarks:
- modelled data
- Details on results:
- ECOSAR Program (v1.11) Results:
===============================
ECOSAR Version 1.11 Results Page
SMILES : CC(=O)CC(=O)N(CC(=O)OCC)c1ccccc1
CHEM : F-37
CAS Num:
ChemID1:
MOL FOR: C14 H17 N1 O4
MOL WT : 263.30
Log Kow: 0.866 (EPISuite Kowwin v1.68 Estimate)
Log Kow: (User Entered)
Log Kow: (PhysProp DB exp value - for comparison only)
Melt Pt: (User Entered for Wat Sol estimate)
Melt Pt: (deg C, PhysProp DB exp value for Wat Sol estimate)
Wat Sol: 3629 (mg/L, EPISuite WSKowwin v1.43 Estimate)
Wat Sol: (User Entered)
Wat Sol: (PhysProp DB exp value)
--------------------------------------
Values used to Generate ECOSAR Profile
--------------------------------------
Log Kow: 0.866 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 3629 (mg/L, EPISuite WSKowwin v1.43 Estimate)
--------------------------------------
ECOSAR v1.11 Class-specific Estimations
--------------------------------------
Esters
Amides
Predicted
ECOSAR Class Organism Duration End Pt mg/L (ppm)
=========================== ================== ======== ====== ==========
Esters : Daphnid 48-hr LC50 379.384
Amides : Daphnid 48-hr LC50 944.092
Applicant's summary and conclusion
- Conclusions:
- Using the ECOSAR v1.11 model the estimated LC50 values for this substance range from 379.384 to 944.092 mg/L.
- Executive summary:
The ECOSAR results for daphnia are as follows:
ECOSAR Program (v1.11) Results:
===============================
ECOSAR Version 1.11 Results Page
SMILES : CC(=O)CC(=O)N(CC(=O)OCC)c1ccccc1
CHEM : F-37
CAS Num:
ChemID1:
MOL FOR: C14 H17 N1 O4
MOL WT : 263.30
Log Kow: 0.866 (EPISuite Kowwin v1.68 Estimate)
Log Kow: (User Entered)
Log Kow: (PhysProp DB exp value - for comparison only)
Melt Pt: (User Entered for Wat Sol estimate)
Melt Pt: (deg C, PhysProp DB exp value for Wat Sol estimate)
Wat Sol: 3629 (mg/L, EPISuite WSKowwin v1.43 Estimate)
Wat Sol: (User Entered)
Wat Sol: (PhysProp DB exp value)
--------------------------------------
Values used to Generate ECOSAR Profile
--------------------------------------
Log Kow: 0.866 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 3629 (mg/L, EPISuite WSKowwin v1.43 Estimate)
--------------------------------------
ECOSAR v1.11 Class-specific Estimations
--------------------------------------
Esters
Amides
Predicted
ECOSAR Class Organism Duration End Pt mg/L (ppm)
=========================== ================== ======== ====== ==========
Esters : Daphnid 48-hr LC50 379.384
Amides : Daphnid 48-hr LC50 944.092
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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