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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07-11 September 2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
Solutions of the test item in water are agglutinated. So it was not possible to prepare a satured and filterable solution. The test item and water were mixed in different ratios to cover the range of complete miscibility. The mixtures were agitated on a roller mixer or on a shaking machine at T = 23 °C overnight and after that conditioned at 20 °C ± 0.5 °C overnight.
The solubility range is between the lowest concentration with undissolved test item and the highest observed concentration with completely dissolved test item.
GLP compliance:
yes (incl. certificate)
Type of method:
other: The method is described in "Principles of method if other than guideline".
Key result
Water solubility:
> 200 - < 300 g/L
Conc. based on:
test mat.
Incubation duration:
ca. 1 d
Temp.:
20 °C
pH:
>= 3.5 - <= 3.8
Conclusions:
Based on visual inspection the solubility of the substance in water is between the lowest observed concentration with completely dissolved test item (200 g/L) and the highest concentration with undissolved test item (300 g/L).

Description of key information

The solubility of the substance in water is between the lowest observed concentration with completely dissolved test item (200 g/L) and the highest concentration with undissolved test item (300 g/L). For the chemical safety assessment, the lower limit is used.

Key value for chemical safety assessment

Water solubility:
200 g/L
at the temperature of:
20 °C

Additional information