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EC number: 946-949-2 | CAS number: -
The %B cells, %T cells, %I-Ak + cells, and %I-Aκ +CD69+ cells were determined by flow cytometry as described in the Experimental Design section of this report. B:T ratios were then calculated. Group means and standard deviations are tabulated below. Test groups that show an increase of 25% or more (≥1.25 fold) when compared to the vehicle control in these LNC surface markers and have an SI value of 1.6 or more are considered dermal sensitizers. All four concentrations of the test article had a positive response, indicating that this test article is a true sensitizer. The positive controls 25% HCA and 0.25% DNCB were also found to be sensitizing.
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