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EC number: 237-354-2
CAS number: 13760-80-0
The oral LD50 value in Wistar rats was established to exceed 2000 mg/kg
The acute oral toxicity potential of the test material to the rat was
investigated in accordance with the standardised guidelines OECD 420 and
EU Method B1 bis under GLP conditions using the Fixed Dose Method.
Following a sighting test during which two animals received test
material at dose levels of 300 mg/kg and 2000 mg/kg respectively, a
further group of four fasted females was given a single oral dose of
test material, as a solution in distilled water, at a dose level of 2000
mg/kg body weight. Clinical signs and body weight
development were monitored during the 14 day observation period of the
study. All animals were subjected to gross necropsy.
No mortality occurred and there were no signs of systemic toxicity. The
animals showed expected gains in body weight during the study and there
were no abnormalities noted at necropsy.
Under the conditions of this study, the oral LD50 value in Wistar rats
was established to exceed 2000 mg/kg body weight.
In accordance with the criteria for classification as defined in Annex
I, Regulation (EC) No 1272/2008, the substance does not require
classification with respect to acute toxicity via the oral route.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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