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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Not reported
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
no
Type of method:
gas saturation method
Key result
Temp.:
23 °C
Vapour pressure:
0.092 Pa
Remarks on result:
other: Temperature 22 to 24 °C
Key result
Temp.:
49 °C
Vapour pressure:
1.36 Pa
Key result
Transition / decomposition:
no

Table 1: Results of Measurement of Evaporation Rate and Vapour Concentration

Temperature (°C)

Sample Measurement No.

Carrier gas flow rate (v × 10^6/m³min^-1)

Evaporation rate (k × 10³/mg min^-1)

Vapour concentration ((k/v)/g m^-3)

22 to 24

1

6.77

0.255

0.00376

56.5

0.264

0.00468

45.2

0.220

0.00487

33.9

0.188

0.00556

0

-

0.00723*

2

67.7

0.262

0.00386

56.5

0.240

0.00426

45.2

0.214

0.00474

33.9

0.188

0.00554

0

-

0.0709*

49

1

67.7

3.44

0.0507

56.5

3.21

0.0569

45.2

3.03

0.0670

33.9

2.66

0.0784

0

-

0.105*

2

67.7

3.42

0.0505

56.5

3.18

0.0563

45.2

2.99

0.0662

33.9

2.66

0.0786

0

-

0.105*

*Saturated vapour pressure which was calculated by extrapolation of flow rate 0 to flow rate dependence of vapour concentration.

 

Table 2: Results of Saturated Vapour Concentration and Vapour Pressure Calculation

Temperature (°C)

Sample Measurement No.

Saturated Vapour Concentration (gm^-3)*

Vapour Pressure (Pa)

22 to 24

1

0.00723

0.0932

2

0.00709

0.0914

Mean

-

0.0923

49

1

0.105

1.36

2

0.105

1.36

Mean

-

1.36

*Saturated vapour pressure which was calculated by extrapolation of flow rate 0 to flow rate dependence of vapour concentration. The value is nominal of saturated vapour concentration after conversion to the volume of gas at 25 °C

Conclusions:
Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 ˚C) and 1.36 Pa at 49 ˚C.
Executive summary:

The vapour pressure of the test material was investigated in a study conducted via methodology similar to that outlined in the standardised guideline OECD 104 using the gas saturation method.

In this method vapour pressure is calculated by measuring vapour concentration (amount of evaporation/volume of gas) while carrier gas (mainly nitrogen) flows in contact with the sample of certain temperature generating saturated vapour of the sample. The determination is done based on the assumption that vapour obeys the ideal gas law.

The evaporation rate of sample is obtained by means of measurement of weight decrease rate of sample by electronic balance and carrier gas flow rate is measured by flow meter to obtain vapour concentration of the sample. The determination was carried out at room temperature and 49 °C

Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 °C) and 1.36 Pa at 49 °C.

Description of key information

The vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 ˚C) and 1.36 Pa at 49 °C.

Key value for chemical safety assessment

Vapour pressure:
0.092 Pa
at the temperature of:
23 °C

Additional information

The vapour pressure of the test material was investigated in a study conducted via methodology similar to that outlined in the standardised guideline OECD 104 using the gas saturation method. The study was assigned a reliability score of 2 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).

In this method vapour pressure is calculated by measuring vapour concentration (amount of evaporation/volume of gas) while carrier gas (mainly nitrogen) flows in contact with the sample of certain temperature generating saturated vapour of the sample. The determination is done based on the assumption that vapour obeys the ideal gas law.

The evaporation rate of sample is obtained by means of measurement of weight decrease rate of sample by electronic balance and carrier gas flow rate is measured by flow meter to obtain vapour concentration of the sample. The determination was carried out at room temperature and 49 °C

Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 °C) and 1.36 Pa at 49 °C.