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PBT assessment

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PBT assessment: overall result

Reference
Name:
α-methyl-1,3-benzodioxole-5-propionaldehyde
Type of composition:
legal entity composition of the substance
State / form:
liquid
Reference substance:
Composition 1
Reference substance:
Composition 1
PBT status:
PBT assessment does not apply
Justification:

Although α-methyl-1,3-benzodioxole-5-propionaldehyde (HLF) fulfills the criteria for toxicity (T) and is also potentially persistent (P) or very persistent (vP), it does not fulfill the criteria for bioaccumulation (B) or very bioaccumulative (vB) and therefore it is not classified as either a PBT or vPvB substance (see ECHA guidance ‘Part C: PBT/vPvB assessment’ version 2.0 of November 2014).

Persistence Assessment

Two studies were conducted to assess the ready biodegradability of the test material (3-(1,3-benzodioxol-5-yl)-2-methylpropanal) in water, i.e. a CO2 evolution test and a manometric respirometry test. In the CO2 evolution test, the test material achieved an average of 24% degradation at day 28, classifying therefore the substance as not readily biodegradable. In the manometric respirometry test, the test material achieved 56 % biodegradation at the end of the 10-day window (days 14 to 24) and 66 % biodegradation after 29 days, classifying therefore the substance as not readily biodegradable but inherently biodegradable. Given that the biodegradability in both tests was <60% within the 28-day period, the substance is regarded as being potentially persistent (P) or very persistent (vP) according to Table C.4-1 of the ECHA guidance on PBT/vPvB assessment.

Bioaccumulation Assessment

The octanol-water coefficient (log Pow) of α-methyl-1,3-benzodioxole-5-propionaldehyde (HLF) is 2.4; this value is lower than the trigger value of 4.5 for bioaccumulative (B) and very bioaccumulative (vB). Therefore it is not bioaccumulative (B) or very bioaccumulative (vB).

Toxicity Assessment

Even though none of the endpoints for aquatic ecotoxicity (NOEC, EC50, LC50 and EC10) are < 0.1 mg/L (the trigger value for toxicity (T)), α-methyl-1,3-benzodioxole-5-propionaldehyde (HLF) does fulfil the toxicity (T) criteria as it is classified as toxic for reproduction (category 2, H361) and because there is other evidence that suggests chronic toxicity/damage to organs (as identified by the classification STOT, category 2, H373) through prolonged or repeated oral exposure.