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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study report): JNJ-119717-AAA (T001036)
- Physical state: solid
Specific details on test material used for the study:
no data

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
isopropanol
Solubility:
44 g/L
Medium:
other: dichloromethane
Solubility:
215 g/L
Medium:
other: 2-propanone
Solubility:
81 g/L
Medium:
dimethylformamide
Solubility:
436 g/L
Medium:
other: N,N-dimethylacetamide
Solubility:
> 20 other: g/100 mL solution
Details on results:
no data

Any other information on results incl. tables

An excess of the solute is equilibrated with the solvent at room temperature for 24 hours.

Applicant's summary and conclusion