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Flammability

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Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 July - 01 October 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)
Deviations:
no
GLP compliance:
yes
Specific details on test material used for the study:
- Batch n°: A14JB3422
- Analytical purity (acid titration): 93.3%
- Expiration date: 30 September 2016
- Storage condition: at room temperature
Test procedure:
burning rate test: preliminary screening test
Remarks on result:
substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

In contact with the flame of the gas burner the test item melted, and turned into a dark brown grey residue.

After removal of the ignition source, no propagation of combustion of the test item was observed.

Interpretation of results:
not classified based on GHS criteria
Conclusions:
The preliminary screening test was performed for the determination of the flammability of JNJ-119717-AAA (T001036).

No propagation of combustion of the test item along 200 mm length of the pile within 2 minutes was observed. According to the guidelines, performance of the burning rate test is not required. Based on the results obtained, the test item is considered ‘not flammable’ or 'not readily combustible'.
Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Although the study was not performed according to an OECD or EC guideline, the used methodology is adequate and sufficient to conclude on the 'flammability of solids' endpoint. However, no information on purity of the substance is reported.
Qualifier:
according to
Guideline:
other: VDI Guideline 2263 Part 1, Burning behaviour: Test Methods for the Determination of the Safety Characteristic of Dusts (May 1990)
Deviations:
no
Qualifier:
according to
Guideline:
other: ESCIS Expert Commission for Safety in the Swiss Chemical Industry, Booklet 1 ”Sicherheitstests fur Chemikalien" (1998)
Deviations:
yes
Remarks:
30 min conditioning instead of 1 hour
GLP compliance:
not specified

There is no spreading of fire (class 1: no ignition at 20 and at 100 deg C).

Interpretation of results:
other: not flammable under the conditions of the test
Conclusions:
The substance is not considered to be flammable since no ignition occurred at 20 °C and at 100 ° C.
Endpoint:
pyrophoric solids
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied
other:
Endpoint:
substances / mixtures which in contact with water emit flammable gases
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Description of key information

The flammability potential of T001036 was determined in a Klimisch 1 GLP study according to the UN N.1 Method.

Based on the results obtained, T001036 is considered ‘not flammable’ or 'not readily combustible'.

Further, based on a theoretical assessment and experience in day-to-day handling and use, the substance can be considered to be not pyrophoric nor flammable in contact with water. Based on the fact that the substance is completely molten at 160°C, the substance is also considered not self-heating.

Key value for chemical safety assessment

Flammability:
not classified

Additional information

A supporting study (PSC, 1985) investigated the burning behaviour of the substance and assigned burning class 1 (no ignition) to the substance, hereby supporting the results obtained in the key study (i.e., not flammable, not readily combustible). This supporting study could not be evaluated for reliability and was assigned Klimisch score 4.

Justification for classification or non-classification

T001036 does not need to be classified as flammable.