Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
12 August - 9 October 2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study (OECD 105).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report Date:
2000

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
Pre-Incubation Temperature for the flask method: 30 +- 1°C, it was 30 +- 2°C during the experiment because of technical reasons
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
not specified
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
- Name of test material (as cited in study report): TH 1165 I
- Physical state: yellow liquid
- Analytical purity: 99.01 %
- Purity test date: 6. march 2000
- Lot/batch No.: 14
- Expiration date of the lot/batch: can be requested from sponsor
- Stability: can be requested from sponsor
- Storage condition of test material: at room temperature

Results and discussion

Water solubility
Water solubility:
6.5 g/L
Temp.:
20

Any other information on results incl. tables

Results for the Determination of the Water Solubility of the Test Item

 sample description  peak area measured mg/L  Dilution factor  calculated g/L  measured pH after Incubation
 72 h  288058  64.5  100  6.4  6
 72 h  287741  64.4  100  6.4  6
 48 h  291055  65.2  100  6.5  6
 48 h  289963  64.9  100  6.5  6
 24 h  289409  64.8  100  6.5  6
 24 h  289011  64.7  100  6.5  6

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
In conclusion, the water solubility of TH 1165 I was calculated to be 6.5 g/L (mean value, 0.03 g/L standard deviation ) at 20°C +-1°C.