Registration Dossier

Administrative data

Description of key information

The key study for acute oral toxicity, which was conducted according to OECD TG 420 and in compliance with GLP, reports an LD50 value of >2000 mg/kg bw (Hameln, 2015). 

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
2 000 mg/kg bw

Additional information

The key study for acute oral toxicity, which was conducted according to OECD TG 420 and in compliance with GLP, reports an LD50 value of >2000 mg/kg bw (Hameln, 2015). One out of four animals died, and there were signs of toxicity including lacrimation, reduced activity, lethargy and mild spasm in hind legs. All animals appeared normal within 48 hours. No macroscopic findings were noted at necropsy.


Justification for selection of acute toxicity – oral endpoint
The study was conducted according to current guideline and in compliance with GLP.

Justification for classification or non-classification

Based on the available data, α-methylenebenzyl acetate does not require classification for acute toxicity according to Regulation (EC) No 1272/2008.