Registration Dossier
Registration Dossier
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EC number: 210-890-4 | CAS number: 625-36-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound: no data available
Hydrolysis product 3-chloropropionic acid: with high probability acutely not harmful to aquatic invertebrates
Hydrolysis product: HCl: Acutely very toxic for aquatic invertebrates (pH dependent).
Key value for chemical safety assessment
Additional information
No data for the parent 3-chloropropionyl chloride (CAS 625-36-5) are available. However, the parent compound 3-chloropropionyl chloride (CAS 625-36-5) rapidly hydrolyses in contact with water and forms 3-chloropropionic acid (107-94-8) and HCL (CAS 7647 -01 -0). Therefore, the acute toxicity to aquatic invertebrates will be assessed based on the information available for the hydrolysis products 3-chloropropionic acid and HCl.
Parent compound 3-chloropropionyl chloride(CAS 625-36-5):
No data available.
Hydrolysis product 3-chloropropionic acid (CAS 107-94-8):
The acute toxicity of the hydrolysis product 3-chloropropionic acid to aquatic invertebrates was tested according to OECD 202 using Daphnia magna as test organism (ECHA, disseminated data, 2015). In this static limit study the 48-h EC50 was determined to be > 100 mg/L (nominal, analytically verified).
Therefore, it can be considered, that the substance is with high probability acutely not harmful to aquatic invertebrates.
Hydrolysis product HCl:
HCl was tested in an acute toxicity test according to OECD 202 with D. magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; MITI, 1999; peer reviewed data: OECD SIDS, 2002). Therefore, based on the available experimental data the hydrolysis product HCl is considered to be acutely very toxic for aquatic invertebrates (pH dependent). These data have not been taken into consideration to evaluate aquatic toxicity as observed effects are caused by a pH-shift in the test medium.
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