Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-992-3 | CAS number: 420-04-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.01 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.032 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.001 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 0.003 mg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 88 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.04 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.004 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.151 mg/kg soil dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 0.5 mg/kg food
- Assessment factor:
- 300
Additional information
Conclusion on classification
Classification-related information
Hydrolysis: hydrolytically stable at pH values of 5, 7 and 9 at 25 °C
Biodegradation: readily biodegradable
Log Pow: - 0.72
Ecotoxicological data
Test data on short-term (acute) toxicity
Fish, short-term, freshwater: LC50 (96 h) = 43.1 mg /L (EPA-660/3-75-009, L. macrochirus; McAllister, 1985)
Invertebrates, short-term, freshwater: EC50 = 3.2 mg a.i./L (OECD 202, D. magna; Adema, 1983)
Algae (green algae), freshwater: EC50 (72 h, growth rate) = 14.7 mg a.i/L (similar OECD 201, P. subcapitata; Seyfried, 2000)
Aquatic plants, freshwater: EC50 (7 d, growth rate) = 5.61 mg a.i./L (OECD 221, L. gibba; Hertl, 2000)
Test data on long-term (chronic) toxicity
Fish, long-term, freshwater: NOEC (21 d) = 3.7 mg/L (OECD 204, O. mykiss; Bowman, 1990)
Invertebrates, long-term, freshwater: NOEC (21 d) = 0.1044 mg/L (EPA OPP 72-4, D. magna; Murrell, 1995)
Algae, freshwater: NOEC (72 h, growth rate) = 2.6 mg a.i/L (similar OECD 201, P. subcapitata; Seyfried, 2000)
Aquatic plants, freshwater: NOEC (7 d, growth rate) = 5.61 mg a.i./L (OECD 221, L. gibba; Hertl, 2000)
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. The substance is readily biodegradable and has a log Pow of -0.72. For short-term toxicity Daphnia magna has been evaluated to be the most sensitive species with an acute EC50 of 3.2 mg/L. The 96-hour LC50 for fish was determined to be = 43.1 mg a.i. /L. In a study similar to OECD 201 with the standard test organism Pseudokirchneriella subcapitata the 72-hour ErC50 and NOEC (growth rate) of the substance was determined to be 28.8 mg/L (nominal, corresponding to 14.7 mg a.i./L) and 5.0 mg/L (nominal, corresponding to 2.6 mg a.i./L), respectively. In a study with the blue-green algae Anabaena flos-aquae (Hertl, 2000) EC50 values below 1 mg/L were determined. However, the study is regarded not valid due to major methodological deficiencies and is hence not considered for the hazard and risk assessment. The lowest long-term result was obtained for Daphnia magna. The 21-day NOEC was found to be 2.6 mg a.i/L. Based on available data, the substance is not classified and labelled for aquatic short-term (acute) toxicity, but as long-term (chronic) toxicity category 3 (H412, “Harmful to aquatic life with long-lasting effects”; based on the long-term result for D. magna) according to Regulation (EC) No 1272/2008 (CLP), , as amended for the eighteenth time in Regulation (EU) 2022/692.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.