Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-080-7 | CAS number: 103-11-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Long-term toxicity on invertebrates towards Daphnia magna with 2-ethylhexyl acrylate (OECD 211, semi-static): 21d-EC10 (growth)= 0.85mg/L ; 21d-EC10 (reproduction)= 0.91mg/L ; 21d-EC50 (mortality)= 1.6 mg/L
Results for
the structurally related n-butyl acrylate and ethyl acrylate for
long-term toxicity towards Daphnia magna :
- Data from the structurally related n-butyl
acrylate:
NOEC (reproduction) = 0.136 mg/L (Daphnia magna, OECD 211, semi-static)
- Data from the structurally related ethyl acrylate:
NOEC (reproduction) = 0.19 mg/L (Daphnia magna, EPA OTS 797.1330,
flow-through)
Key value for chemical safety assessment
Additional information
The effects of the long-term exposure of Daphnia magna to 2-ethylhexyl acrylate according to OECD Guideline 211 have been studied (Charles River, 2020).
The test was performed in a closed system with a semi-static renewal. Five test concentrations ranging from 5.6, 10, 18, 32 and 56% of a saturated solution prepared at a loading rate of 50 mg/L (TMW concentrations: 0.21, 0.44, 0.85, 1.4, 2.8 mg/L respectively) were employed. The effects values were related to TWM concentrations and are given as follows: 21d-EC10 (growth)= 0.85mg/L ; 21d-EC10 (reproduction)= 0.91mg/L ; 21d-EC50 (mortality)= 1.6 mg/L
In addition, data on the structurally related ethyl acrylate and n-butyl acrylate 21 -day chronic toxicity studies are available (BAMM 1997, BASF SE 2009).
A 21 -day Daphnia magna Reproduction Test sponsored by The Acrylate REACH Task Force was performed with n-Butyl acrylate under semi-static conditions in accordance with OECD TG 211 and GLP regulations (BASF SE, 2009). Nominal test concentrations were 0, 0.1, 0.22, 0.46, 1.0, and 2.2 mg/L. Since the mean values of n-Butyl Acrylate in M4-medium were found to be in the range of 9.3 – 80.0 % of the nominal concentrations, the effect concentrations were based on the time-weighted mean analytically detected concentrations. The most sensitive effect values were concerning reproduction: NOEC (reproduction) = 0.136 mg/L; LOEC (reproduction) = 0.457 mg/L. Survival of the parent or young daphnia was not effected, but the growth of the parent animals: NOEC (body length) = 0.457 mg/L; LOEC (body length) = 1.226 mg/L.
In addition, a 21-day chronic study with Ethyl acrylate in Daphnia magna was conducted under flow-through conditions according to EPA OTS 797.1330 (BAMM, 1997). Nominal exposure concentrations ranged from 0.38 to 6.0 mg/L. Mean measured test concentrations ranged from 0.19 to 3.2 mg/L. Effect concentrations based on measured values were as follows: EC50 was 0.5 mg/L; NOEC (reproduction) = 0.19 mg/L; LOEC (reproduction) = 0.45 mg/L and MATC (reproduction) = 0.29 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.