Registration Dossier
Registration Dossier
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EC number: 204-822-2 | CAS number: 127-08-2
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No specific test guideline was reported; however, a scientifically defensible approach was used to conduct the study.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 969
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 962
Materials and methods
- Principles of method if other than guideline:
- Single oral toxicity is estimated by the gastric intubation of groups of five non-fasted, Carworth-Wistar rats, four to five weeks of age and 90 to 120 grams in weight, which have been reared in the laboratory own colony and mantained from time of weaning on Rockland rat diet, complete. Dose: 3.25g/kg (2.48-4.26). The observation period was 14 days.
- GLP compliance:
- no
- Test type:
- other: metod described
- Limit test:
- no
Test material
- Reference substance name:
- Potassium acetate
- EC Number:
- 204-822-2
- EC Name:
- Potassium acetate
- Cas Number:
- 127-08-2
- Molecular formula:
- C2H4O2.K
- IUPAC Name:
- potassium acetate
- Details on test material:
- - Name of test material (as cited in study report): Potassium acetate
- Molecular formula (if other than submission substance): KOOCCH3
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Carworth-Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 3.25 g/kg (2.48-4.26)
- No. of animals per sex per dose:
- Five male rats per group
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- ca. 3.25 other: g/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Potassium acetate LD50 is 3.25 g/kg (2.48-4.26).
- Executive summary:
Single oral toxicity is estimated by the gastric intubation of groups of five non-fasted, Carworth-Wistar rats, four to five weeks of age and 90 to 120 grams in weight, which have been reared in the laboratory own colony and mantained from time of weaning on Rockland rat diet, complete. Dose: 3.25g/kg (2.48-4.26). The observation period was 14 days.
Potassium acetate LD50is 3.25 g/kg (2.48-4.26).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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