Registration Dossier
Registration Dossier
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EC number: 233-046-7 | CAS number: 10025-87-3
Endpoint summary
Administrative data
Description of key information
Study scientifically not necessary:
“In water, phosphoryl trichloride hydrolyzes to phosphoric acid and hydrochloric acid with t1/2 < 10 seconds (Riess, 2002): POCl3 + 3 H2O → H3PO4 + 3 HCl” (OECD SIDS for phosphoryl trichloride, 2004).
The corresponding pH value of phosphoryl trichloride at 25 °C is approximately 1 (at 5 g/L).
Phosphoryl trichloride is listed on Annex VI of Regulation (EC) No 1272/2008 with classification as Skin corr. 1A, H314: Causes severe skin burns and eye damage.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
The data requirement is waived due to the harmonised classification of phosphoryl trichloride as Skin Corr. 1A, H314: Causes severe skin burns and eye damage, and the severity of the skin reactions seen in the acute dermal toxicity study and the dermal irritation study. Dermal exposure to phosphoryl trichloride will be dominated by local irritation/corrosion and skin sensitisation is considered to be unlikely.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
No data.
Justification for classification or non-classification
No classification is proposed in the absence of any experimental studies or relevant findings from human exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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