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EC number: 278-770-4
CAS number: 77804-81-0
Mouse Lymphoma cells (L5178Y TK+/-) were treated with the test substance
at five or six concentrations in the range of 11.7 to 375 microgram/mL.
Precipitation of the test substance was detectable at dose level 187.5
and 375 microgram/mL. The solvent control gave mutant frequencies within
the normal range. The positive controls gave marked increases in the
mutant frequency, both in the presence or absence of metabolic
activation, indicating the satisfactory performance of the test system.
The test substance demonstrated no statistically significant or dose
related increases in mutant frequency at any dose level, either with or
without metabolic activation, thus indicating that the test item is not
mutagenic under the conditions tested.
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