Registration Dossier
Registration Dossier
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EC number: 200-908-9 | CAS number: 75-85-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only secondary literature
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Patty's Industrial Hygiene and Toxicology
- Author:
- Rowe and McCollister
- Year:
- 1 982
- Bibliographic source:
- Clayton and Clayton (eds.), Vol.2C, 3rd ed. (1982), John Wiley & Sons, New York, 4604 - 4605, 4608, 4701
Materials and methods
- Principles of method if other than guideline:
- Acute dermal toxicity, no further details
- GLP compliance:
- not specified
- Test type:
- other: standard acute method (in vivo)
Test material
- Reference substance name:
- 2-methylbutan-2-ol
- EC Number:
- 200-908-9
- EC Name:
- 2-methylbutan-2-ol
- Cas Number:
- 75-85-4
- Molecular formula:
- C5H12O
- IUPAC Name:
- 2-methylbutan-2-ol
Constituent 1
Test animals
- Species:
- rabbit
Administration / exposure
- Type of coverage:
- occlusive
- Duration of exposure:
- 24 hours
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 1 720 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
