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Diss Factsheets
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EC number: 203-982-0 | CAS number: 112-53-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data obtained from a secondary source
- Principles of method if other than guideline:
- Method: other: (measured)
- Water solubility:
- 4 mg/L
- Temp.:
- 25 °C
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
Water solubility value of 4 mg/l was reported for the substance - Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009-09-24
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test procedure in accordance with national standard methods (ASTM) without GLP.
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E 1148
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 1 mg/L
- Temp.:
- 23 °C
- pH:
- 5.5
- Remarks on result:
- other: Standard Deviation for these Data : +/- 0.1 mg/L
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
The water solubility was determined to be 1.0 mg/l at 23 °C. - Executive summary:
Dodecan-1 -ol was determined according ASTM E 1148. The water solubility was determined to be 1.0 mg/l at 23 °C.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This result was obtained from a secondary source which is peer-reviewed.
- GLP compliance:
- not specified
- Type of method:
- other: slow-stir procedure
- Water solubility:
- 1.93 mg/L
- Temp.:
- 20 °C
- Remarks on result:
- other: The pH of the solution is not stated, but since the substance is only a very weak acid (pKa ca. 16) it is anticipated to create a neutral solution.
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
A water solubility value of 1.93 mg/L was reported in a collection of reliable data which has been subject to peer-review. The result is considered to be reliable. - Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data obtained from a secondary source
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
- Water solubility:
- 1.7 - 2.9 mg/L
- Temp.:
- 16 °C
- Remarks on result:
- other: The pH of the solution is not stated, but since the substance is only a very weak acid (pKa > 16) it is anticipated to create a neutral solution.
- Water solubility:
- 2.9 mg/L
- Temp.:
- 34 °C
- Remarks on result:
- other: The pH of the solution is not stated, but since the substance is only a very weak acid (pKa > 16) it is anticipated to create a neutral solution.
- Conclusions:
- Interpretation of results: slightly soluble (0.1-100 mg/L)
Water solubility of the substance was obtained from a secondary source
Referenceopen allclose all
Measurement
(triple determination)
Results: 1.1 mg/L / 1.0 mg/L / 1.0 mg/L
Mean Concentration in Water: 1.0 mg/L
Standard Deviation for These Data: ±0.1 mg/L
Description of key information
The water solubility of a commercial sample of dodecan-1-ol is 1 mg/L at 23°C and pH 5.5.
Key value for chemical safety assessment
- Water solubility:
- 1 mg/L
- at the temperature of:
- 23 °C
Additional information
The solubility of 1 mg/L at 23°C and pH 5.5 was determined for the substance with the use of a flask method in accordance with ASTM E 1148. The result is considered to be reliable.
It is supported by a value of 1.93 mg/L, taken from a reliable and definitive reference source for solubility data (Letinski, 2002) and consistent results from other reference sources.
The value taken from literature for pure alcohol is used in exposure modelling.
Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:
As chain length increases, water solubility decreases, because the free energy required for a molecule to dissolve becomes less favourable for larger molecules.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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