Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
266-013-0
CAS no.:
65996-79-4
Index number:
Molecular formula:
C25H22O
SMILES:
OC1=CC=CC=C1.C1C=CC2=C1C=CC=C2.C1=CC2=CC=CC=C2C=C1
InChI:
InChI=1S/C10H8.C9H8.C6H6O/c1-2-6-10-8-4-3-7-9(10)5-1;1-2-5-9-7-3-6-8(9)4-1;7-6-4-2-1-3-5-6/h1-8H;1-6H,7H2;1-5,7H
Type of substance:
UVCB
Origin:
Organic
Registered compositions:
5
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP01) approved by the European Union, this substance may cause genetic defects and may cause cancer.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may be fatal if swallowed and enters airways, is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life, causes damage to organs through prolonged or repeated exposure, is a flammable liquid and vapour, causes serious eye irritation, is harmful if swallowed, is harmful if inhaled, is suspected of causing cancer, is suspected of damaging fertility or the unborn child, causes skin irritation, may cause respiratory irritation and may cause drowsiness or dizziness.

Breakdown of all 129 C&L notifications submitted to ECHA

Muta. 1B H340 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Asp. Tox. 1 H304
Flam. Liq. 3 H226
Eye Irrit. 2 H319
Skin Irrit. 2 H315
Aquatic Acute 1 H400
Aquatic Chronic 1 H410
Acute Tox. 4 H302
Acute Tox. 4 H332
STOT SE 3 H335
Carc. 2 H351
STOT SE 3 H336
Carc. 1A H350
Aquatic Chronic 2 H411
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (57.14% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (57.14% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 2 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1+ tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of chemicals, closed batch processing in synthesis or formulation, in materials as fuel sources, with limited exposure to unburned product to be expected and manual maintenance (cleaning and repair) of machinery.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of substance into small containers and batch processing in synthesis or formulation with opportunity for exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, transfer of chemicals, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure and transfer of substance into small containers.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, of substances in closed systems with minimal release and manufacturing of the substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites and as processing aid.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not handle until all safety precautions have been read and understood; take actions to prevent static discharges; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Collect spillage. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Do not induce vomiting. If on skin: wash with soap and water.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Petrochemia-Blachownia Sp. z o.o., Szkolna 15 47-225 Kędzierzyn - Koźle Poland
  • RAIN CARBON BVBA, Vredekaai 18 9060 Zelzate Belgium

Substance names and other identifiers

[The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F). Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.]
The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F) Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.
C&L Inventory
Light Oil Extract Residues, high boiling
The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F) Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.
C&L Inventory, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Solvent naphtha (coal)
EC Inventory, C&L Inventory, REACH pre-registration, Other, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures
Solvent naphtha (coal); Light Oil Extract Residues, high boiling [The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130o C to 210o C (266oF to 410oF). Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.]
The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F) Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.
CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
Solvent naphtha (coal); Light Oil Extract Residues, high boiling
The distillate from either high temperature coal tar, coke oven light oil, or coal tar oil alkaline extract residue having an approximate distillation range of 130°C to 210°C (266°F to 410°F) Composed primarily of indene and other polycyclic ring systems containing a single aromatic ring. May contain phenolic compounds and aromatic nitrogen bases.
Workplace Signs - minimum requirements & signs on containers and pipes, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes
(Destillaat, mis saadakse kas kõrgtemperatuurse kivisöetõrva, koksiahju kerge õli või kivisöetõrva õli leeliselise ekstraktsiooni jääkide destilleerimisel ja nende keemistemperatuur on umbes vahemikus 130–210 °C. Koosneb peamiselt indeenist ja teistest polütsüklilistest ühenditest, kaasa arvatud ka üksik aromaatne tsükkel. Võib sisaldada fenooliühendeid ja aromaatseid lämmastikaluseid.) (et)
C&L Inventory
[Aukštatemperatūrio akmens anglių deguto, koksavimo krosnies lengvosios alyvos arba akmens anglių deguto alyvos šarminio ekstrahavimo likučio distiliatas, kurio distiliavimo temperatūra maždaug nuo 130 °C iki 210 °C (nuo 266 °F iki 410 °F) Jį sudaro daugiausia indenas ir kitos policiklinės sistemos, turinčios vieną aromatinį ciklą. Gali turėti fenolio junginių ir aromatinių azotinių bazių.] (lt)
C&L Inventory
[Destilat iz lakog ulja visoko-temp. koksne peći katrana kam. ugljena ili iz alk. ekstrakta ostatka ulja ugljenog katrana koji ima približno područje destilacije od 130 °C do 210 °C. Primarno sastavljen od indena i drugih policikličkih prstenastih sustava koji sadrže jedan aromatski prsten. Mogu sadržavati spojeve fenola i aromatske dušikove baze.] (hr)
C&L Inventory
[Destilat iz visokotemperaturnega premogovega katrana, lahkega olja koksaren ali ostanka iz alkalnega ekstakta olja premogovega katrana, z območjem destilacije približno med 130 °C in 210 °C. Pretežno ga sestavljajo inden in druge spojine s policiklično obročasto strukturo, ki imajo en sam aromatski obroč. Lahko vsebuje fenolne spojine in aromatske dušikove baze.] (sl)
C&L Inventory
[Destillat aus entweder Hochtemperaturkohlenteer, Koksofenleichtöl oder Rückstand aus alkalischem Extrakt von Kohlenteeröl mit einem ungefähren Destillationsbereich von 130 °C bis 210 °C; besteht in erster Linie aus Inden und anderen polycyclischen Ringsystemen mit einem einzigen aromatischen Ring; kann Phenolverbindungen und aromatische Stickstoffbasen enthalten] Leichtöl-Extraktrückstände, hochsiedend (de)
C&L Inventory
[Destillat enten fra høytemperaturstenkulltjære, koksovnslettolje eller alkaliske ekstraksjonsrester av stenkulltjæreoljer, med omtrentlig destillasjonsintervall fra 130 °C til 210 °C (266 °F til 410 °F). Består hovedsakelig av inden og andre polysykliske ringsystemer som inneholder en enkel aromatisk ring. Kan inneholde fenolforbindelser og aromatiske nitrogenbaser.] (no)
C&L Inventory
[Destilát buď z vysokoteplotního černouhelného dehtu, koksárenského lehkého oleje nebo ze zbytků po alkalické extrakci lehkého oleje, s destilačním rozmezím přibližně 130 °C až 210 °C. Je složen převážně z indenu a dalších polycyklických systémů s jedním aromatickým jádrem. Může obsahovat fenolické sloučeniny a aromatické dusíkaté báze.] (cs)
C&L Inventory
[Destilát z vysokoteplotného uhoľného dechtu, koksárenského ľahkého oleja alebo zvyšku po alkalickom prepieraní oleja z uhoľného dechtu. Má teplotu varu v rozmedzí približne od 130 °C až 210 °C. Pozostáva predovšetkým z indénu a iných polycyklických zlúčenín obsahujúcich jeden aromatický kruh. Môže obsahovať fenolové zlúčeniny a aromatické dusíkaté zásady.] (sk)
C&L Inventory
[Destilāts iegūts augstā temperatūrā no akmeņogļu darvas vai koksa krāsnī no vieglās eļļas, vai kā akmeņogļu darvas eļļas sārma ekstrakcijas atlikums, aptuvenā destilācijas temperatūra no 130°C līdz 210°C (266°F līdz 410°F) Sastāv galvenokārt no indēna un citām policiklisku gredzenu sistēmām, kurās ietilpst viens atsevišķs aromātiskais cikls. Var ietilpt fenola savienojumi un aromātiskās slāpekļa bāzes.] (lv)
C&L Inventory
[Destylat z wysokotemperaturowej smoły węglowej albo z oleju lekkiego pochodzenia koksowniczego albo z pozostałości alkalicznego ekstraktu oleju smołowego, destylujący w zakresie temperatur ok. od 130°C do 210°C (266°F do 410°F). Składa się głównie z indenu i innych wielopierścieniowych układów zawierających pojedynczy pierścień aromatyczny. Może zawierać pochodne fenolowe i aromatyczne zasady azotowe.] (pl)
C&L Inventory
[Distillat obtenu à partir de goudron de houille à haute température, d'huile légère de four à coke ou du résidu de l'extraction alcaline d'huile de goudron de houille, et dont l'intervalle d'ébullition se situe approximativement entre 130°C et 210°C. Se compose principalement d'indène et d'autres systèmes polycycliques contenant un cycle aromatique. Peut contenir des composés phénoliques et des bases aromatiques azotées]; résidus d'extraction d'huile légère, haut point d'ébullition (fr)
C&L Inventory
[Magas hőmérsékletű kőszénkátrány, kokszolókemence könnyűolaj vagy kőszénkátrány olaj alkáli extrakciós maradékának desztillátuma, melynek közelítő desztillációs tartománya 130°C-tól 210°C-ig (266°F-től 410°F-ig) terjed. Elsősorban indénből és más policiklusos gyűrűs rendszerekből áll, melyek egy aromás gyűrűt tartalmaznak. Tartalmazhatnak még fenolvegyületeket és aromás nitrogén bázisokat is.] (hu)
C&L Inventory
[Produsele de distilare ale gudronului de cărbune la temperatură înaltă, ale ţiţeiului uşor din cuptorul de cocsificare sau ale reziduului extracţiei alcaline a gudronului de cărbune având un punct de distilare cuprins între 130°C şi 210°C (266°F şi 410°F). Compus cu precădere din inden sau alte sisteme policiclice cu inele conţinând un singur inel aromatic. Poate conţine compuşi fenolici şi baze azotate aromatice.] (ro)
C&L Inventory
[Το απόσταγμα είτε από λιθανθρακόπισσα υψηλής θερμοκρασίας ή από ελαφρό έλαιο κλιβάνου παραγωγής κοκ ή από υπόλειμμα αλκαλικού εκχυλίσματος ελαίου λιθανθρακόπισσας, που αποστάζει μεταξύ 130°C και 210°C περίπου. Αποτελείται κυρίως από ινδένιο και άλλα πολυκυκλικά συστήματα που περιέχουν ένα μόνον αρωματικό δακτύλιο. Μπορεί να περιέχει φαινολικές ενώσεις και αρωματικές αζωτούχες βάσεις.] (el)
C&L Inventory
[Дестилат от високотемпературен каменовъглен катран, лека фракция от коксови пещи или фракция от остатъчни алкални екстракти на каменовъглен катран с приблизителен интервал на дестилация от 130°C до 210ºС (266°F до 410°F). Състои се основно от инден и други полициклени пръстенови структури, съдържащи само един ароматен пръстен. Възможно е да съдържа фенолни съединения и ароматни азотни основи. ] (bg)
C&L Inventory
Benzinsko otapalo (ugljen) (hr)
C&L Inventory
benzínové rozpúšťadlo (uhoľné) (sk)
C&L Inventory
Destilado de alcatrão de carvão de alta temperatura, de óleo leve de forno de coque ou de resíduo do extracto alcalino de óleo de alcatrão de carvão, com um intervalo de destilação aproximado de 130 °C a 210 °C. É constituído principalmente por indeno e outros sistemas anulares policíclicos com um só anel aromático. Pode conter compostos fenólicos e bases aromáticas azotadas. (pt)
C&L Inventory
destilado de alquitrán de hulla a elevada temperatura, aceite ligero del horno de coque o residuo del extracto alcalino del aceite de alquitrán de hulla con un intervalo de destilación aproximado de 130 °C a 210 °C; compuesto principalmente de indeno y otros sistemas de anillos policíclicos con un solo anillo aromático; puede contener compuestos fenólicos y bases nitrogenadas aromáticas (es)
C&L Inventory
Destillat från antingen högtemperaturstenkolstjära, koksugnslättolja eller alkaliska extraktionsåterstoder av stenkolstjärolja, med ungefärligt destillationsintervall från 130 °C till 210 °C. Består främst av inden och andra polycykliska ringsystem innehållande en enda aromatisk ring. Kan innehålla fenolföreningar och aromatiska kvävebaser. (sv)
C&L Inventory
Destillatet fra enten højtemperatursstenkulstjære, koksovnsletolie eller alkalisk ekstraktionsrest af stenkulstjæreolie, med et omtrentligt destillationsinterval fra 130 °C til 210 °C (266 ºF til 410 ºF). Sammensat primært af inden og andre polycycliske ringsystemer indeholdende en enkelt aromatisk ring. Kan indeholde phenolforbindelser og aromatiske nitrogenbaser. (da)
C&L Inventory
Distillato di catrame di carbone ad alta temperatura, di olio leggero da forno a coke, o di residuo dell'estrazione alcalina di olio leggero di catrame con punto di ebollizione nell'intervallo 130°-210°C ca. (da 266°F a 410°F). È costituito principalmente da indene ed altri composti policiclici contenenti un singolo anello aromatico. Può contenere composti fenolici e basi aromatiche azotate . (it)
C&L Inventory
Ekst. ostaci lakog ulja, visoko-vrijući (hr)
C&L Inventory
extrakčné zvyšky z ľahkého oleja s vysokou teplotou varu (sk)
C&L Inventory
Het destillaat dat wordt verkregen uit het alkalische extractieresidu van hoge-temperatuur-koolteer, lichte olie uit de cokesoven of koolteerolie, met een destillatietraject van ongeveer 130°C tot 210°C. Bestaat voornamelijk uit indeen en andere polycyclische ringsystemen die één aromatische ring bevatten. Kan fenolverbindingen en aromatische stikstofbasen bevatten. (nl)
C&L Inventory
Kerge õli ekstraktsioonijäägid, kõrge keemistemperatuuriga (et)
C&L Inventory
Kevytöljyuutejäännökset, korkealla kiehuva (fi)
C&L Inventory
Könnyűolaj extrakciós maradékok, magas forráspontú (hu)
C&L Inventory
Lahustibensiin (kivisüsi) (et)
C&L Inventory
Lengvosios alyvos ekstrahavimo likučiai, aukštatemperatūriai (lt)
C&L Inventory
lettolje ekstraksjonsrester, høytkokende (no)
C&L Inventory
Lichte olie, extractieresidu, hoogkokende fractie (nl)
C&L Inventory
Liuotinbensiini (kivihiili) (fi)
C&L Inventory
Lättolja, extraktionsåterstoder, högkokande (sv)
C&L Inventory
Nafta (carvão) (pt)
C&L Inventory
nafta disolvente (hulla) (es)
C&L Inventory
nafta solvente (carbone) (it)
C&L Inventory
Oldószer benzin (kőszén) (hu)
C&L Inventory
ostanki ekstrakta lahkega olja, visoko vrelišče (sl)
C&L Inventory
Pozostałości po ekstrakcji oleju lekkiego, wysokowrzące (pl)
C&L Inventory
Produsele de distilare ale gudronului de cărbune la temperatură înaltă, ale ţiţeiului uşor din cuptorul de cocsificare sau ale reziduului extracţiei alcaline a gudronului de cărbune având un punct de distilare cuprins între 130°C şi 210°C (266°F şi 410°F). Compus cu precădere din inden sau alte sisteme policiclice cu inele conţinând un singur inel aromatic. Poate conţine compuşi fenolici şi baze azotate aromatice. (mt)
C&L Inventory
residui di estrazione di olio leggero, altobollenti (it)
C&L Inventory
residuos del extracto de aceite ligero, alto punto de ebullición (es)
C&L Inventory
Resíduos de extracção de óleo leve, alto ponto de ebulição (pt)
C&L Inventory
Reziduuri de extracţie ale ţiţeiului uşor cu puncte de fierbere la temperaturi înalte. (mt)
C&L Inventory
résidus d'extraction d'huile légère, haut point d'ébullition (fr)
C&L Inventory
Solvant naphta (houille);résidus d'extrait d'huile légère, haut point d'ébullition;[distillat de goudron de houille à haute température, huile légère de four à coke, ou de résidu d'extrait alcalin d'huile de goudron de houille, dont l'intervalle de distillation est compris approximativement entre 130 et 210 oC (entre 266 et 410 oF). Principalement composé d'indène et d'autres systèmes polycycliques à un seul noyau aromatique. Peut contenir des composés phénoliques et des bases azotées aromatiques.] (fr)
C&L Inventory
Solvent fracţia nafta (cărbune) (mt)
C&L Inventory
solvent nafta (premog) (sl)
C&L Inventory
Solvent Naphtha (Kohle) (de)
C&L Inventory
Solventnafta (akmens anglys) (lt)
C&L Inventory
Solventnafta (akmeņogles) (lv)
C&L Inventory
Solventnafta (kol) (sv)
C&L Inventory
Solventnafta (kool) (nl)
C&L Inventory
solventnafta (kull) (no)
C&L Inventory
solventnaphtha (kul); Syrefri letolie, højtkogende (da)
C&L Inventory
Solventní nafta (černouhelná) (cs)
C&L Inventory
Solwent nafta (węgiel) (pl)
C&L Inventory
Tisle, joka saadaan joko korkean lämpötilan kivihiilitervasta, koksiuunikevytöljystä tai kivihiilitervan alkalisesta uutejäännöksestä. Tislausalue noin 130°C–210°C (266°F–410°F). Pääasiallinen koostumus: indeeni ja muut polysykliset rengasyhdisteet, joissa on yksi ainoa aromaattinen rengas. Voi sisältää fenoliyhdisteitä ja aromaattisia typpiemäksiä. (fi)
C&L Inventory
vieglās eļļas ekstrakcijas atlikums ar augstu viršanas temperatūru (lv)
C&L Inventory
Zbytky z extrakce lehkého oleje, vysokovroucí (cs)
C&L Inventory
δΔιαλύτης νάφθα (άνθρακα) (el)
C&L Inventory
Υπολείμματα εκχύλισης ελαφρού ελαίου, υψηλού σημείου ζέσεως (el)
C&L Inventory
Остатъчни продукти от екстракция на лека фракция, с висока температура на кипене (bg)
C&L Inventory
Солвент нафта (каменни въглища) (bg)
C&L Inventory
1H-indene; naphthalene; phenol
Other
648-020-00-4
Index number
C&L Inventory
65996-79-4
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Cosmetic Products Regulation, Annex II - Prohibited Substances, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II, Workplace Signs - minimum requirements & signs on containers and pipes, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Carc and Muta Directive, Annex I - Substances, Mixtures & Processes, Physical, Biological and Chemical Agents & Processes and Work

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 7 studies submitted
  • 7 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [7]
C Form
Other (67%), Not specified (33%) [3]
C Odour
Characteristic of aromatic compounds (67%), Other (33%) [6]
C Substance type
Organic (67%), Petroleum product (17%), Other (17%) [6]

Type of Study provided
Studies with data
Key study 4 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 4 studies processed
R Melting / freezing point
-30 - 45 °C [4]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Melting / freezing point at 101 325 Pa
4.8 - 32.2 °C

Boiling point

Study results
  • 16 studies submitted
  • 13 studies processed
R Boiling point
77 - 430.5 °C @ 101.3 - 101.325 kPa [13]

Type of Study provided
Studies with data
Key study 15 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Boiling point at 101 325 Pa
80.09 - 182 °C

Density

Study results
  • 13 studies submitted
  • 2 studies processed
R Relative density
0.894 - 0.94 @ 15.556 - 20 °C [2]

Type of Study provided
Studies with data
Key study 13
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Relative density at 20°C
0.876 - 0.98

Vapour pressure

Study results
  • 9 studies submitted
  • 7 studies processed
R Vapour pressure
2 - 41 hPa @ 20 - 100 °C [7]

Type of Study provided
Studies with data
Key study 9
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Vapour pressure
1.86 - 100 hPa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 2 studies processed
R Log Pow
2.8 - 6.5 @ 25 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Log Kow (Log Pow)
2.13 - 5.8 @ 20 °C

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
108 mg/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 3 summaries submitted
  • 3 summaries processed
Water solubility
20 - 1 880 mg/L @ 20 - 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 5 studies submitted
  • 5 studies processed
R Flash point
36.5 - 76 °C @ 101.325 kPa [5]

Type of Study provided
Studies with data
Key study 5
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
46.4 °C

Auto flammability

Study results
  • 2 studies submitted
  • 2 studies processed
R Autoflammability / self-ignition
409 - 505 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
457 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 11 studies submitted
  • 11 studies processed
R Other:
1.81 [1]
R dynamic viscosity (in mPa s)
2.39 [1]
R kinematic viscosity (in mm²/s)
0.95 - 3.033 [9]

Type of Study provided
Studies with data
Key study 11
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Static viscosity at 20 °C
1.6 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 3 studies submitted
  • 2 studies processed
C Interpretation of results
Inherently biodegradable (50%), Not readily biodegradable (50%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Biodegradation in water
Under test conditions no biodegradation observed (67%), Readily biodegradable (33%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
162

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 1 µg/L (1)
Intermittent releases (freshwater) -
Marine water 1 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) No hazard identified (1)
Sediment (freshwater) No hazard identified (1)
Sediment (marine water) No hazard identified (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No hazard identified (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 days) 580 - 6 100 µg/L [2]
LL50 (4 days) 730 - 6 300 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
730 µg/L

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 3 studies submitted
  • 2 studies processed
P/RResults
EC50 (48 h) 760 - 2 900 µg/L [2]
EC50 (24 h) 1.4 mg/L [1]
EL50 (48 h) 910 - 3 200 µg/L [2]
EL50 (24 h) 1.6 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
910 µg/L
EC50 / LC50 for marine invertebrates
1.4 mg/L

Long–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 4 studies processed
P/RResults
EC10 (7 days) 570 µg/L [1]
EL10 (7 days) 810 µg/L [1]
EL10 (6 days) 490 - 850 µg/L [2]
EL50 (7 days) 2.64 - 2.72 mg/L [2]
LL50 (6 days) 1.35 - 3.3 mg/L [2]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
490 µg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 6 studies processed
P/RResults
EC50 (4 days) 1 mg/L [1]
EC50 (72 h) 940 - 4 600 µg/L [2]
NOEC (4 days) 940 µg/L [1]
NOEC (72 h) 300 - 370 µg/L [2]
EC10 (72 h) 960 µg/L [1]

Type of Study provided
Studies with data
Key study 6
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
1.3 mg/L
EC10 or NOEC for freshwater algae
460 µg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (56 days) 47.2 mg/L [1]
NOEC (28 days) 47.2 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
47.2 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.31 mg/m³ repeated dose toxicity
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: (DNEL) 2.31 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 160.23 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 340 µg/kg bw/day -
Acute /short term: High hazard (no threshold derived)
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 690 µg/m³ repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: (DNEL) 690 µg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 143.5 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 280 µg/kg bw/day repeated dose toxicity
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
Local Effects
Long-term: Hazard unknown (no further information necessary as no exposure expected)
Acute /short term: Hazard unknown (no further information necessary as no exposure expected)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 30 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 25.6 mg/kg bw/day acute toxicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
No bioaccumulation potential
Absorption values
Oral: 100 %
Dermal: 0.1 %
Inhalation: 50 %

Acute toxicity

Study results
oral
  • 5 studies submitted
  • 3 studies processed
P/RResults
LD50 512 - 5 000 mg/kg bw (rat) [5]
M/CInterpretations of results
Other [3]

Type of Study provided
oral
Studies with data
Key study 3
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 10 studies submitted
  • 4 studies processed
P/RResults
LC50 (6 h) 1.723 mg/L air (rat) [1]
LC50 (6 h) 284 - 353 ppm (rat) [2]
LC50 (4 h) 5.14 - 30 mg/L air (rat) [4]
M/CInterpretations of results
Other [4]

inhalation
Studies with data
Key study 4
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 4 studies processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
LD50 2 000 mg/kg bw (rabbit) [3]
M/CInterpretations of results
Other [4]

dermal
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Oral route:
Adverse effect observed LD50 590 mg/kg bw
Inhalation route:
Adverse effect observed LC50 1 972 mg/m³
Dermal route:
No adverse effect observed LD50 8 260 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 6
Supporting study 4
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 4
Supporting study 5
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin
Adverse effect observed (irritating)
Eye
Adverse effect observed (irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 3 summaries processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 5 studies processed
P/RResults
NOAEL (rat): 4 - 625 mg/kg bw/day [9]
LOAEL (rat): 25 - 1 250 mg/kg bw/day [3]

Type of Study provided
Study data: oral
Studies with data
Key study 5
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Study data: inhalation
  • 4 studies submitted
  • 4 studies processed
P/RResults
NOAEC (rat): 96 - 2 355 mg/m³ air [3]
NOAEC (rat): 30 - 625 ppm [3]
NOAEC (mouse): 5.1 ppm [1]
LOAEC (rat): 4.71 mg/L air [1]
LOAEC (rat): 1 250 ppm [1]

Study data: inhalation
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Oral route - systemic effects:
Adverse effect observed NOAEL 4 mg/kg bw/day (subacute, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)
Inhalation route - local effects:
Adverse effect observed NOAEC 27.6 mg/m³ (subchronic, mouse)

Genetic toxicity

Study results
Study data: in vitro
  • 16 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 14
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Toxicity - InVivo
Adverse effect observed (positive)

Carcinogenicity

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Oral route:
Adverse effect observed LOAEL 25 mg/kg bw/day (chronic, mouse)
Inhalation route:
Adverse effect observed LOAEC 960 mg/m³ (subchronic, mouse)

Toxicity to reproduction

Study results
Study data: reproduction
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 5
Data waiving
no waivers
Study data: developmental
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 10
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 60 mg/kg bw/day (subacute, rat)

Neurotoxicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant