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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2001
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Bundesministerium für Land- und Forstwirtschaft Umwelt und Wasserwirtschaft, Vienna, Austria
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
439-590-3
EC Name:
-
Cas Number:
12158-75-7
Molecular formula:
Hill: Cu2(OH)3NO3 CAS:
IUPAC Name:
copper trihydroxynitrate
Details on test material:
CAS# 12158-75-7, Batch 060248

Test animals

Species:
rabbit
Strain:
other: CRL: CD (SD) IGS BR
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
not specified
Duration of exposure:
24 h
Doses:
2000 mg / kg bw
No. of animals per sex per dose:
5 M + 5 F
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mL/kg bw

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Remarks:
Migrated information
Conclusions:
the LD_{50} for acute dermal toxicity is higher than 2000 mg/kg bw