Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Specific investigations: other studies
Administrative data
- Endpoint:
- specific investigations: other studies
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: primary source unkown in due it is not published
Data source
Reference
- Reference Type:
- secondary source
- Title:
- COPPER VOLUNTARY RISK ASSESSMENT
- Author:
- Delbeke et al.
- Year:
- 2 008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 428
- Deviations:
- yes
- Remarks:
- see free text
- Principles of method if other than guideline:
- see free text
- GLP compliance:
- not specified
- Type of method:
- in vitro
- Endpoint addressed:
- dermal absorption
Test material
- Reference substance name:
- see free text
- IUPAC Name:
- see free text
- Details on test material:
- see free text
Constituent 1
Test animals
- Species:
- other: n.a.
Administration / exposure
- Route of administration:
- other: see free text
- Vehicle:
- other: see free text
- Duration of treatment / exposure:
- see free text
- Frequency of treatment:
- see free text
- Post exposure period:
- see free text
- No. of animals per sex per dose:
- see free text
Results and discussion
- Details on results:
- Given the available studies provide no consistent evidence that dermal absorption is greater for soluble than for insoluble copper substances, a dermal absorption factor of 0.3% is also proposed
Applicant's summary and conclusion
- Conclusions:
- SCHER conclusion: "For dermal absorption, 0.3 % was
taken as the best estimate absorption factor from unpublished in vitro studies. For dry
copper substances 0.03 % was used, as a default."
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
